Introduction：Basic information about CAS 1283658-71-8|Methylamino-PEG4-acid HCl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methylamino-PEG4-acid HCl |
|---|
| CAS Number | 1283658-71-8 | Molecular Weight | 279.330 |
|---|
| Density | 1.1±0.1 g/cm3 | Boiling Point | 405.5±40.0 °C at 760 mmHg |
|---|
| Molecular Formula | C12H25NO6 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 199.1±27.3 °C |
|---|
Names
| Name | Methylamino-PEG4-acid |
|---|
| Synonym | More Synonyms |
|---|
Methylamino-PEG4-acid HCl BiologicalActivity
| Description | Methylamino-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 405.5±40.0 °C at 760 mmHg |
|---|
| Molecular Formula | C12H25NO6 |
|---|
| Molecular Weight | 279.330 |
|---|
| Flash Point | 199.1±27.3 °C |
|---|
| Exact Mass | 279.168182 |
|---|
| LogP | -1.62 |
|---|
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
|---|
| Index of Refraction | 1.458 |
|---|
| InChIKey | NVNPCETYZYDTLZ-UHFFFAOYSA-N |
|---|
| SMILES | CNCCOCCOCCOCCOCCC(=O)O |
|---|
Synonyms
| 5,8,11,14-Tetraoxa-2-azaheptadecan-17-oic acid |
| MFCD28064328 |
