CAS 150272-33-6|Benzyl-PEG2-MS

Introduction:Basic information about CAS 150272-33-6|Benzyl-PEG2-MS, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBenzyl-PEG2-MS
CAS Number150272-33-6Molecular Weight274.33
Density/Boiling Point/
Molecular FormulaC12H18O5SMelting Point/
MSDS/Flash Point/

Names

NameBenzyl-PEG3-Mes
SynonymMore Synonyms

Benzyl-PEG2-MS BiologicalActivity

DescriptionBenzyl-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Molecular FormulaC12H18O5S
Molecular Weight274.33
InChIKeyJITMDLGZONISDY-UHFFFAOYSA-N
SMILESCS(=O)(=O)OCCOCCOCc1ccccc1

Synonyms

Benzyl-PEG2-MS
CAS 150044-43-2|diethyl 4,4'-dinitro-[1,1'-biphenyl]-2,2'-dicarboxylate
CAS 150407-54-8|Dirpopylene Glycol Methyl Propylene Ether
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