CAS 150972-72-8|7,8-Didehydrocimigenol
Introduction：Basic information about CAS 150972-72-8|7,8-Didehydrocimigenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 7,8-Didehydrocimigenol | ||
|---|---|---|---|
| CAS Number | 150972-72-8 | Molecular Weight | 486.683 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 621.8±55.0 °C at 760 mmHg |
| Molecular Formula | C30H46O5 | Melting Point | / |
| MSDS | / | Flash Point | 329.8±31.5 °C |
Names
| Name | 7,8-Didehydrocimigenol |
|---|---|
| Synonym | More Synonyms |
7,8-Didehydrocimigenol BiologicalActivity
| Description | 7,8-Didehydrocimigenol is an active triterpenoid that can be isolated from Cimicifugae rhizoma. 7,8-Didehydrocimigenol inhibits TNF-α-induced VCAM-1 expression, inhibits NF-kB activity and phosphorylation of ERK1/2 and Akt, increases PPAR-γ expression. 7,8-Didehydrocimigenol can be used for the research of cardiovascular disorders such as atherosclerosis[1]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Cell Cycle/DNA Damage >>PPAR |
| References | [1]. Mun L, et al. 7,8-didehydrocimigenol from Cimicifugae rhizoma inhibits TNF-α-induced VCAM-1 but not ICAM-1expression through upregulation of PPAR-γ in human endothelial cells. Food Chem Toxicol. 2011 Jan;49(1):166-72. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 621.8±55.0 °C at 760 mmHg |
| Molecular Formula | C30H46O5 |
| Molecular Weight | 486.683 |
| Flash Point | 329.8±31.5 °C |
| Exact Mass | 486.334534 |
| LogP | 5.31 |
| Vapour Pressure | 0.0±4.1 mmHg at 25°C |
| Index of Refraction | 1.601 |
Synonyms
| (1S,2R,3R,7R,9S,12R,14R,17R,18R,19R,21R,22S)-22-(2-Hydroxy-2-propanyl)-3,8,8,17,19-pentamethyl-23,24-dioxaheptacyclo[19.2.1.01,18.03,17.04,14.07,12.012,14]tetracos-4-ene-2,9-diol |
| 10,12a-Epoxy-2H,5H-cyclopropa[1',8'a]naphth[2',1':4,5]indeno[2,1-b]oxepin-2,13-diol, 1,3,4,6,7,7a,7b,8,9,10,11,13,13a,15,15a-pentadecahydro-11-(1-hydroxy-1-methylethyl)-1,1,7a,8,13a-pentamethyl-, (2S,4aR,5aR,7aR,7bR,8R,10R,11S,12aS,13R,13aR,15aR)- |
