CAS 1536327-95-3|Carboxyrhodamine 110-PEG3-Azide

Introduction:Basic information about CAS 1536327-95-3|Carboxyrhodamine 110-PEG3-Azide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCarboxyrhodamine 110-PEG3-Azide
CAS Number1536327-95-3Molecular Weight574.6
Density/Boiling Point/
Molecular FormulaC58H60N12O14Melting Point/
MSDS/Flash Point/

Names

NameCarboxyrhodamine 110-PEG3-Azide

Carboxyrhodamine 110-PEG3-Azide BiologicalActivity

DescriptionCarboxyrhodamine 110-PEG3-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Molecular FormulaC58H60N12O14
Molecular Weight574.6
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