CAS 155319-91-8|Mangafodipir

Introduction:Basic information about CAS 155319-91-8|Mangafodipir, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMangafodipir
CAS Number155319-91-8Molecular Weight691.379
Density/Boiling Point/
Molecular FormulaC22H30N4O14P2.MnMelting Point/
MSDS/Flash Point/

Names

NameMangafodipir

Mangafodipir BiologicalActivity

DescriptionMangafodipir, hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir shows no negative interference with the tumoricidal activity of chemotherapy[1][2].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
References

[1]. Karlsson JOG, et al. Mangafodipir a Selective Cytoprotectant - with Special Reference to Oxaliplatin and Its Association to Chemotherapy-Induced Peripheral Neuropathy (CIPN). Transl Oncol. 2017 Aug;10(4):641-649.

[2]. Wang C. Mangafodipir trisodium (MnDPDP)-enhanced magnetic resonance imaging of the liver and pancreas. Acta Radiol Suppl. 1998;415:1-31.

Chemical & Physical Properties

Molecular FormulaC22H30N4O14P2.Mn
Molecular Weight691.379
InChIKeyQDQFSBKXQQZVTB-UHFFFAOYSA-L
SMILESCc1ncc(COP(=O)([O-])[O-])c(CN(CCN(CC(=O)[O-])Cc2c(COP(=O)([O-])[O-])cnc(C)c2O)CC(=O)[O-])c1O.[H+].[H+].[H+].[H+].[Mn+2]
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