Introduction:Basic information about CAS 156706-72-8|N6-DiMethylaMinoMethylidene isoguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N6-DiMethylaMinoMethylidene isoguanosine |
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| CAS Number | 156706-72-8 | Molecular Weight | 338.32 |
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| Density | 1.8±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C13H18N6O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N6-DiMethylaMinoMethylidene isoguanosine |
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| Synonym | More Synonyms |
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N6-DiMethylaMinoMethylidene isoguanosine BiologicalActivity
| Description | N6-Dimethylaminomethylidene isoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
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| Molecular Formula | C13H18N6O5 |
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| Molecular Weight | 338.32 |
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| Exact Mass | 338.133881 |
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| LogP | -2.79 |
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| Index of Refraction | 1.772 |
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| InChIKey | VBDFGPWFFLJGON-PZYHSTABSA-N |
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| SMILES | CN(C)C=Nc1[nH]c(=O)nc2c1ncn2C1OC(CO)C(O)C1O |
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Synonyms
| MFCD25542456 |
| 3-Hydroadenosine, N-[(dimethylamino)methylene]-2-oxo- |
| N-[(Dimethylamino)methylene]-2-oxo-3-hydroadenosine |