CAS 156706-72-8|N6-DiMethylaMinoMethylidene isoguanosine

Introduction:Basic information about CAS 156706-72-8|N6-DiMethylaMinoMethylidene isoguanosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN6-DiMethylaMinoMethylidene isoguanosine
CAS Number156706-72-8Molecular Weight338.32
Density1.8±0.1 g/cm3Boiling Point/
Molecular FormulaC13H18N6O5Melting Point/
MSDS/Flash Point/

Names

NameN6-DiMethylaMinoMethylidene isoguanosine
SynonymMore Synonyms

N6-DiMethylaMinoMethylidene isoguanosine BiologicalActivity

DescriptionN6-Dimethylaminomethylidene isoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Density1.8±0.1 g/cm3
Molecular FormulaC13H18N6O5
Molecular Weight338.32
Exact Mass338.133881
LogP-2.79
Index of Refraction1.772
InChIKeyVBDFGPWFFLJGON-PZYHSTABSA-N
SMILESCN(C)C=Nc1[nH]c(=O)nc2c1ncn2C1OC(CO)C(O)C1O

Synonyms

MFCD25542456
3-Hydroadenosine, N-[(dimethylamino)methylene]-2-oxo-
N-[(Dimethylamino)methylene]-2-oxo-3-hydroadenosine
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