Introduction：Basic information about CAS 518044-49-0|Hydroxy-PEG3-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hydroxy-PEG3-acid |
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| CAS Number | 518044-49-0 | Molecular Weight | 266.288 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 420.7±40.0 °C at 760 mmHg |
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| Molecular Formula | C9H18O6 | Melting Point | / |
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| MSDS | / | Flash Point | 155.5±20.8 °C |
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Names
| Name | PEG4-acid |
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| Synonym | More Synonyms |
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Hydroxy-PEG3-acid BiologicalActivity
| Description | Hydroxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 420.7±40.0 °C at 760 mmHg |
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| Molecular Formula | C9H18O6 |
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| Molecular Weight | 266.288 |
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| Flash Point | 155.5±20.8 °C |
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| Exact Mass | 266.136566 |
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| LogP | -2.07 |
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| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
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| Index of Refraction | 1.466 |
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| InChIKey | NJUMHPXJVKDMAW-UHFFFAOYSA-N |
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| SMILES | O=C(O)CCOCCOCCOCCO |
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Safety Information
Synonyms
| MFCD22574805 |
| 1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid |
| 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-hydroxy- |
