Introduction：Basic information about CAS 86770-77-6|Benzyl-PEG5-amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Benzyl-PEG5-amine |
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| CAS Number | 86770-77-6 | Molecular Weight | 327.416 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 429.7±40.0 °C at 760 mmHg |
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| Molecular Formula | C17H29NO5 | Melting Point | / |
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| MSDS | / | Flash Point | 210.7±21.0 °C |
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Names
| Name | Benzyl-PEG5-Amine |
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| Synonym | More Synonyms |
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Benzyl-PEG5-amine BiologicalActivity
| Description | Benzyl-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 429.7±40.0 °C at 760 mmHg |
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| Molecular Formula | C17H29NO5 |
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| Molecular Weight | 327.416 |
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| Flash Point | 210.7±21.0 °C |
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| Exact Mass | 327.204559 |
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| LogP | -0.03 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.498 |
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Synonyms
| 2,5,8,11,14-Pentaoxahexadecan-16-amine, 1-phenyl- |
| MFCD28976656 |
| 1-Phenyl-2,5,8,11,14-pentaoxahexadecan-16-amine |
