CAS 873061-79-1|Ganoderone A

Introduction:Basic information about CAS 873061-79-1|Ganoderone A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGanoderone A
CAS Number873061-79-1Molecular Weight454.684
Density1.1±0.1 g/cm3Boiling Point568.0±50.0 °C at 760 mmHg
Molecular FormulaC30H46O3Melting Point/
MSDS/Flash Point311.4±26.6 °C

Names

NameGanoderone A
SynonymMore Synonyms

Ganoderone A BiologicalActivity

DescriptionGanoderone A is a triterpene compound that can be isolated from the fruiting body of Ganoderma pfeifferi and Ganoderma calidophilum. Ganoderone A has antiviral activity against HSV with IC50 value of 0.3 µg/mL. Ganoderone A has potential applications in viral infections and tumors[1][2][3].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Anti-infection >>HSVResearch Areas >>Infection
Target

HSV:0.3 μg/mL (IC50)

In VitroGanoderone A 对 K562、BEL7402 和 SGC790 细胞系展现出细胞毒性活性,IC50 值分别为 7.62 µM、6.28 µM 和 3.55 µM[3]。
References

[1]. Niedermeyer TH, et al. Antiviral Terpenoid Constituents of Ganoderma pfeifferi. J Nat Prod. 2005 Dec;68(12):1728-31.  

[2]. Huang S Z, et al. Anti-allergic prenylated hydroquinones and alkaloids from the fruiting body of Ganoderma calidophilum[J]. RSC advances, 2016, 6(25): 21139-21147.

[3]. Huang SZ, et al. Lanostane-type triterpenoids from the fruiting body of Ganoderma calidophilum. Phytochemistry. 2017 Nov;143:104-110.  

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point568.0±50.0 °C at 760 mmHg
Molecular FormulaC30H46O3
Molecular Weight454.684
Flash Point311.4±26.6 °C
Exact Mass454.344696
LogP6.79
Vapour Pressure0.0±3.5 mmHg at 25°C
Index of Refraction1.542
InChIKeySDAWCNCFVWQZDP-GOUGDUPLSA-N
SMILESCC(=CCCC(C)C1CCC2(C)C3=C(CCC12C)C1(C)CCC(=O)C(C)(C)C1CC3=O)CO

Synonyms

Lanosta-8,24-diene-3,7-dione, 26-hydroxy-, (24E)-
(24E)-26-Hydroxylanosta-8,24-diene-3,7-dione
GANODERONE A
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