CAS 910050-95-2|2’-O-Methyl-5-hydroxymethyluridine

Introduction:Basic information about CAS 910050-95-2|2’-O-Methyl-5-hydroxymethyluridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2’-O-Methyl-5-hydroxymethyluridine
CAS Number910050-95-2Molecular Weight288.25
Density/Boiling Point/
Molecular FormulaC11H16N2O7Melting Point/
MSDS/Flash Point/

Names

Name2'-O-Methyl-5-hydroxyMethyluridine

2’-O-Methyl-5-hydroxymethyluridine BiologicalActivity

Description2’-O-Methyl-5-hydroxymethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Molecular FormulaC11H16N2O7
Molecular Weight288.25
InChIKeyZJQLVUOUHLNLDA-FDDDBJFASA-N
SMILESCOC1C(O)C(CO)OC1n1cc(CO)c(=O)[nH]c1=O
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