Introduction:Basic information about CAS 959961-96-7|Bevasiranib, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bevasiranib |
|---|
| CAS Number | 959961-96-7 | Molecular Weight | / |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | / | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
Bevasiranib BiologicalActivity
| Description | Bevasiranib is a siRNA designed to silence the genes that produce vascular endothelial growth factor (VEGF). It is widely accepted that vascular endothelial growth factor (VEGF) is a key component in the pathogenesis of choroidal neo-vascularization (CNV), which is a precursor to wet age-related macular degeneration (wet AMD). |
|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Protein Tyrosine Kinase/RTK >>VEGFR |
|---|
| References | [1]. Garba AO, Mousa SA. Bevasiranib for the treatment of wet, age-related macular degeneration. Ophthalmol Eye Dis. 2010;2:75-83. [2]. Dejneka NS, Wan S, Bond OS, Kornbrust DJ, Reich SJ. Ocular biodistribution of bevasiranib following a single intravitreal injection to rabbit eyes. Mol Vis. 2008;14:997-1005. |
|---|
Chemical & Physical Properties
| No Any Chemical & Physical Properties |