CAS 112430-64-5|Ganoderic acid TN

Introduction:Basic information about CAS 112430-64-5|Ganoderic acid TN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGanoderic acid TN
CAS Number112430-64-5Molecular Weight512.721
Density1.1±0.1 g/cm3Boiling Point625.5±55.0 °C at 760 mmHg
Molecular FormulaC32H48O5Melting Point/
MSDS/Flash Point193.1±25.0 °C

Names

NameGanoderic acid TN
SynonymMore Synonyms

Ganoderic acid TN BiologicalActivity

DescriptionGanoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM)[1].
Related CatalogSignaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>Infection
References

[1]. Qinchang Zhu, et al.Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194.  

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point625.5±55.0 °C at 760 mmHg
Molecular FormulaC32H48O5
Molecular Weight512.721
Flash Point193.1±25.0 °C
Exact Mass512.350159
LogP7.87
Vapour Pressure0.0±4.1 mmHg at 25°C
Index of Refraction1.555
InChIKeyYCWGPALSXRBKTM-ZBJMKSMZSA-N
SMILESCC(=O)OC1CC(C(C)CCC=C(C)C(=O)O)C2(C)CC=C3C(=CCC4C3(C)CCC(O)C4(C)C)C12C

Synonyms

(3β,15α,24E)-15-Acetoxy-3-hydroxylanosta-7,9(11),24-trien-26-oic acid
Lanosta-7,9(11),24-trien-26-oic acid, 15-(acetyloxy)-3-hydroxy-, (3β,15α,24E)-
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