Introduction：Basic information about CAS 1188407-46-6|Emtricitabine triphosphate tetrasodium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Emtricitabine triphosphate tetrasodium salt |
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| CAS Number | 1188407-46-6 | Molecular Weight | / |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C8H9FN3Na4O12P3S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | (-)-Emtricitabine Triphosphate Tetrasodium Salt |
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BiologicalActivity
| Description | Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However，Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427)，a nucleoside reverse transcriptase inhibitor，targeting to HIV and HBV[1]. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>HIVResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>HBVSignaling Pathways >>Anti-infection >>Reverse Transcriptase |
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| References | [1]. Frasca K, et al. Emtricitabine triphosphate in dried blood spots is a predictor of viral suppression in HIV infection and reflects short-term adherence to antiretroviral therapy. J Antimicrob Chemother. 2019 May 1;74(5):1395-1401. [2]. Bang LM, et al. Emtricitabine: an antiretroviral agent for HIV infection. Drugs. 2003;63(22):2413-24; discussion 2425-6. |
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Chemical & Physical Properties
| Molecular Formula | C8H9FN3Na4O12P3S |
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| InChIKey | UVCVKFWKKXBGTF-YPNYOHIOSA-J |
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| SMILES | Nc1nc(=O)n(C2CSC(COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O2)cc1F.[Na+].[Na+].[Na+].[Na+] |
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