Introduction：Basic information about CAS 1189560-96-0|Biotin-PEG3-CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Biotin-PEG3-CH2COOH |
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| CAS Number | 1189560-96-0 | Molecular Weight | 433.520 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 769.1±60.0 °C at 760 mmHg |
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| Molecular Formula | C18H31N3O7S | Melting Point | / |
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| MSDS | / | Flash Point | 419.0±32.9 °C |
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Names
| Name | Biotin-PEG3-CH2COOH |
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| Synonym | More Synonyms |
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Biotin-PEG3-CH2COOH BiologicalActivity
| Description | Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 769.1±60.0 °C at 760 mmHg |
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| Molecular Formula | C18H31N3O7S |
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| Molecular Weight | 433.520 |
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| Flash Point | 419.0±32.9 °C |
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| Exact Mass | 433.188263 |
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| LogP | -1.79 |
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| Vapour Pressure | 0.0±5.7 mmHg at 25°C |
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| Index of Refraction | 1.523 |
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Synonyms
| 13-Oxo-17-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-3,6,9-trioxa-12-azaheptadecan-1-oic acid |
| 3,6,9-Trioxa-12-azaheptadecan-1-oic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo- |
| MFCD30749255 |
