Introduction：Basic information about CAS 125562-30-3|Methyl-PEG9-bromide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Methyl-PEG9-bromide |
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| CAS Number | 125562-30-3 | Molecular Weight | 491.412 |
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| Density | 1.2±0.0 g/cm3 | Boiling Point | 498.1±0.0 °C at 760 mmHg |
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| Molecular Formula | C19H39BrO9 | Melting Point | / |
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| MSDS | / | Flash Point | 208.4±0.0 °C |
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Names
| Name | m-PEG9-bromide |
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| Synonym | More Synonyms |
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Methyl-PEG9-bromide BiologicalActivity
| Description | m-PEG9-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 1.2±0.0 g/cm3 |
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| Boiling Point | 498.1±0.0 °C at 760 mmHg |
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| Molecular Formula | C19H39BrO9 |
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| Molecular Weight | 491.412 |
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| Flash Point | 208.4±0.0 °C |
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| Exact Mass | 490.177734 |
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| LogP | -0.88 |
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| Vapour Pressure | 0.0±0.0 mmHg at 25°C |
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| Index of Refraction | 1.462 |
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| InChIKey | UVVCGSZTSMUNGX-UHFFFAOYSA-N |
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| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCBr |
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Synonyms
| 28-Bromo-2,5,8,11,14,17,20,23,26-nonaoxaoctacosane |
| 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosane, 28-bromo- |
| MFCD28950767 |
