CAS 1268135-96-1|Benzyl-PEG2-amine

Introduction:Basic information about CAS 1268135-96-1|Benzyl-PEG2-amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBenzyl-PEG2-amine
CAS Number1268135-96-1Molecular Weight195.258
Density/Boiling Point/
Molecular FormulaC11H17NO2Melting Point/
MSDS/Flash Point/

Names

NameBenzyl-PEG2-Amino

Benzyl-PEG2-amine BiologicalActivity

DescriptionBenzyl-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Molecular FormulaC11H17NO2
Molecular Weight195.258
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