CAS 141410-98-2|Edobacomab

Introduction:Basic information about CAS 141410-98-2|Edobacomab, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameEdobacomab
CAS Number141410-98-2Molecular Weight/
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Names

NameEdobacomab

Edobacomab BiologicalActivity

DescriptionEdobacomab (E5) is a mouse anti-endotoxin monoclonal IgM antibody. Edobacomab ca be uesd for the research of sepsis caused by Gram-negative bacterial infections[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Others >>Others
In VitroProlgolimab can bind endotoxin and neutralize it with subsequent attenuate inflammatory response and improved outcome[2].
References

[1]. Kobayashi H, et, al. [Phase I study of edobacomab (E5) in patients with gram-negative sepsis]. Kansenshogaku Zasshi. 1994 Jan;68(1):59-80.  

[2]. Angus DC, et, al. E5 murine monoclonal antiendotoxin antibody in gram-negative sepsis: a randomized controlled trial. E5 Study Investigators. JAMA. 2000 Apr 5;283(13):1723-30.  

Chemical & Physical Properties

No Any Chemical & Physical Properties
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