Introduction:Basic information about CAS 142864-19-5|Enlimomab, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Enlimomab |
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| CAS Number | 142864-19-5 | Molecular Weight | / |
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Names
Enlimomab BiologicalActivity
| Description | Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research[1] [2] . |
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| Related Catalog | Research Areas >>Inflammation/ImmunologyResearch Areas >>Neurological DiseaseSignaling Pathways >>Cytoskeleton >>Integrin |
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| In Vitro | 在全血中,Enlimomab 以补体依赖的方式激活静息中性粒细胞[1]。 |
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| References | [1]. J Vuorte, et al. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood. J Immunol. 1999 Feb 15;162(4):2353-7. [2]. [2]Gregory J del Zoppo. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci. 2010 Oct;1207:143-8. |
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Chemical & Physical Properties
| No Any Chemical & Physical Properties |