CAS 142864-19-5|Enlimomab

Introduction:Basic information about CAS 142864-19-5|Enlimomab, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameEnlimomab
CAS Number142864-19-5Molecular Weight/
Density/Boiling Point/
Molecular Formula/Melting Point/
MSDS/Flash Point/

Names

NameEnlimomab

Enlimomab BiologicalActivity

DescriptionEnlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research[1] [2] .
Related CatalogResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological DiseaseSignaling Pathways >>Cytoskeleton >>Integrin
In Vitro在全血中,Enlimomab 以补体依赖的方式激活静息中性粒细胞[1]。
References

[1]. J Vuorte, et al. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood. J Immunol. 1999 Feb 15;162(4):2353-7.  

[2]. [2]Gregory J del Zoppo. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci. 2010 Oct;1207:143-8.  

Chemical & Physical Properties

No Any Chemical & Physical Properties
CAS 1428523-91-4|PTB7
CAS 1428728-83-9|Axitinib Impurity 3
Recommended......
TOP