CAS 1951438-84-8|Propargyl-PEG6-acid

Introduction:Basic information about CAS 1951438-84-8|Propargyl-PEG6-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePropargyl-PEG6-acid
CAS Number1951438-84-8Molecular Weight348.389
Density1.1±0.1 g/cm3Boiling Point462.8±45.0 °C at 760 mmHg
Molecular FormulaC16H28O8Melting Point/
MSDS/Flash Point157.6±22.2 °C

Names

NamePropargyl-PEG6-acid
SynonymMore Synonyms

Propargyl-PEG6-acid BiologicalActivity

DescriptionPropargyl-PEG6-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker
Target

Cleavable

In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Anandan Palani, et al. Insulin-incretin conjugates. WO2017160669A1.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point462.8±45.0 °C at 760 mmHg
Molecular FormulaC16H28O8
Molecular Weight348.389
Flash Point157.6±22.2 °C
Exact Mass348.178406
LogP-1.52
Vapour Pressure0.0±2.5 mmHg at 25°C
Index of Refraction1.469
InChIKeyXRSJYQQOJNYUDV-UHFFFAOYSA-N
SMILESC#CCOCCOCCOCCOCCOCCOCCC(=O)O

Synonyms

4,7,10,13,16,19-Hexaoxadocos-21-yn-1-oic acid
MFCD28950778
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