Introduction：Basic information about CAS 201049-37-8|Epothilone E, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Epothilone E |
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| CAS Number | 201049-37-8 | Molecular Weight | 509.65536 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 715.5±60.0 °C at 760 mmHg |
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| Molecular Formula | C26H39NO7S | Melting Point | / |
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| MSDS | / | Flash Point | 386.5±32.9 °C |
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Names
| Name | epothilone E |
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| Synonym | More Synonyms |
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Epothilone E BiologicalActivity
| Description | Epothilone E is a related compound of epothilone, which inhibits microtubule protein function and blocks cell division, and has anti-tumor activity[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Microtubule/TubulinSignaling Pathways >>Cytoskeleton >>Microtubule/Tubulin |
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| References | [1]. Susan Goodin, et al. Epothilones: mechanism of action and biologic activity. J Clin Oncol. 2004 May 15;22(10):2015-25. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 715.5±60.0 °C at 760 mmHg |
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| Molecular Formula | C26H39NO7S |
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| Molecular Weight | 509.65536 |
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| Flash Point | 386.5±32.9 °C |
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| Exact Mass | 509.244720 |
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| LogP | 1.75 |
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| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
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| Index of Refraction | 1.543 |
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| InChIKey | FCCNKYGSMOSYPV-OKOHHBBGSA-N |
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| SMILES | CC(=Cc1csc(CO)n1)C1CC2OC2CCCC(C)C(O)C(C)C(=O)C(C)(C)C(O)CC(=O)O1 |
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Synonyms
| 4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-, (1S,3S,7S,10R,11S,12S,16R)- |
| (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-3-{(1E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]-1-propen-2-yl}-8,8,10,12-tetramethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione |
