Introduction：Basic information about CAS 2055014-94-1|Propargyl-PEG8-acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Propargyl-PEG8-acid |
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| CAS Number | 2055014-94-1 | Molecular Weight | 436.494 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 531.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H36O10 | Melting Point | / |
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| MSDS | / | Flash Point | 171.9±23.6 °C |
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Names
| Name | Propargyl-PEG8-acid |
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| Synonym | More Synonyms |
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Propargyl-PEG8-acid BiologicalActivity
| Description | Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria[1]. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Antibody-drug Conjugate >>ADC LinkerSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Suzanne AKERS-RODRIGUEZ, et al. Compositions and methods for the treatment of bacterial infections. WO2019126353A2. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 531.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H36O10 |
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| Molecular Weight | 436.494 |
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| Flash Point | 171.9±23.6 °C |
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| Exact Mass | 436.230835 |
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| LogP | -2.23 |
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| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
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| Index of Refraction | 1.469 |
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| InChIKey | QZQUQXNQKWZDNM-UHFFFAOYSA-N |
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| SMILES | C#CCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O |
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Safety Information
Synonyms
| MFCD28976699 |
| 4,7,10,13,16,19,22,25-Octaoxaoctacos-27-yn-1-oic acid |
