CAS 688360-06-7|Xanthohumol I
Introduction：Basic information about CAS 688360-06-7|Xanthohumol I, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Xanthohumol I | ||
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| CAS Number | 688360-06-7 | Molecular Weight | / |
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Names
| Name | Xanthohumol I |
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Xanthohumol I BiologicalActivity
| Description | Xanthohumol I, a chalkone, is a derivative of Xanthohumol (HY-N1067). Xanthohumol is a Cholinesterase (ChE) inhibitor, which inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) wih IC50s of 71.34 μM and 32.67 μM, respectively. The hydroxy compound of Xanthohumol (3-hydroxy-xanthohumol), also shoes inhibitory effect on AChE and BChE with IC50s of 51.25 μM and 63.07 μM[1]. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Neuronal Signaling >>AChE |
| Target | AChE BChE |
| References | [1]. Orhan IE, et al. Molecular modeling and in vitro approaches towards cholinesterase inhibitory effect of some natural xanthohumol, naringenin, and acyl phloroglucinol derivatives. Phytomedicine. 2018 Mar 15;42:25-33. |
Chemical & Physical Properties
| InChIKey | PUJSPQKGZNTZCR-RMKNXTFCSA-N |
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| SMILES | COc1cc(O)c2c(c1C(=O)C=Cc1ccc(O)cc1)OC(C(C)(C)O)C2 |
