CAS 862893-75-2|Ganoderic acid TR

Introduction:Basic information about CAS 862893-75-2|Ganoderic acid TR, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGanoderic acid TR
CAS Number862893-75-2Molecular Weight468.668
Density1.1±0.1 g/cm3Boiling Point618.6±55.0 °C at 760 mmHg
Molecular FormulaC30H44O4Melting Point/
MSDS/Flash Point341.9±28.0 °C

Names

NameGanoderic acid TR
SynonymMore Synonyms

Ganoderic acid TR BiologicalActivity

DescriptionGanoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC50 values of 10.9 and 4.6 μM, respectively[1].
Related CatalogSignaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>Infection
Target

IC50: 10.9 (H5N1), 4.6 μM (H1N1)[1]

References

[1]. Zhu Q, et al. Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point618.6±55.0 °C at 760 mmHg
Molecular FormulaC30H44O4
Molecular Weight468.668
Flash Point341.9±28.0 °C
Exact Mass468.323975
LogP6.72
Vapour Pressure0.0±4.1 mmHg at 25°C
Index of Refraction1.563
InChIKeySNZQBBATMLGADX-SKONXDPFSA-N
SMILESCC(=CCCC(C)C1CC(O)C2(C)C3=CCC4C(C)(C)C(=O)CCC4(C)C3=CCC12C)C(=O)O

Synonyms

Lanosta-7,9(11),24-trien-26-oic acid, 15-hydroxy-3-oxo-, (15α,24E)-
(15α,24E)-15-Hydroxy-3-oxolanosta-7,9(11),24-trien-26-oic acid
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