Introduction：Basic information about CAS 874208-90-9|m-PEG6-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG6-Boc |
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| CAS Number | 874208-90-9 | Molecular Weight | 424.526 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 467.7±40.0 °C at 760 mmHg |
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| Molecular Formula | C20H40O9 | Melting Point | / |
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| MSDS | / | Flash Point | 197.2±27.4 °C |
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Names
| Name | m-PEG7-t-butyl ester |
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| Synonym | More Synonyms |
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m-PEG6-Boc BiologicalActivity
| Description | m-PEG6-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs Alkyl/ether |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 467.7±40.0 °C at 760 mmHg |
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| Molecular Formula | C20H40O9 |
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| Molecular Weight | 424.526 |
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| Flash Point | 197.2±27.4 °C |
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| Exact Mass | 424.267242 |
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| LogP | -0.73 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.447 |
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Synonyms
| 2-Methyl-2-propanyl 2,5,8,11,14,17,20-heptaoxatricosan-23-oate |
| MFCD28950751 |
| 2,5,8,11,14,17,20-Heptaoxatricosan-23-oic acid, 1,1-dimethylethyl ester |
