(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid CAS 291775-59-2

Introduction：Basic information about (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid CAS 291775-59-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Basic information

• Product Name: (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
• Synonyms: (3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-(Tert-butoxycarbonyl)-2-azabicyclo-[2.2.1]-heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%;2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 2-(1,1-diMethylethyl) ester, (1R,3S,4S)-;(1R,3S,4S)-3-[(2-methylpropoxy)carbonyl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid;Ledipasvir INT 2;Ledipasvir Impurity 14
• CAS: 291775-59-2
• MF: C12H19NO4
• MW: 241.28
• EINECS: 808-164-2
• Product Categories: Pharmaceuticalintermediates
• Mol File: 291775-59-2.mol

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Chemical Properties

• Melting point: 147-152 °C
• Boiling point: 371.0±25.0 °C(Predicted)
• density: 1.232±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• pka: 4.05±0.20(Predicted)
• form: powder
• Appearance: White to off-white Solid
• Optical Rotation: [α]22/D -170±10°, c = 1 in chloroform
• Major Application: peptide synthesis
• InChI: InChI=1S/C12H19NO4/c1-12(2,3)17-11(16)13-8-5-4-7(6-8)9(13)10(14)15/h7-9H,4-6H2,1-3H3,(H,14,15)/t7-,8+,9-/m0/s1
• InChIKey: IFAMSTPTNRJBRG-YIZRAAEISA-N
• SMILES: [C@]12([H])C[C@]([H])(CC1)[C@@H](C(O)=O)N2C(OC(C)(C)C)=O

Safety Information

• Hazard Codes: Xi,N
• Risk Statements: 61-36/37/38
• Safety Statements: 53-26-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• Storage Class: 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Aquatic Acute 1 Eye Irrit. 2 Repr. 1B Skin Irrit. 2 STOT SE 3

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Usage And Synthesis

Uses

(1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-??daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants.