Introduction：Basic information about (R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine CAS 608142-27-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine Basic information
| Product Name: | (R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine |
| Synonyms: | (R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine;(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine;(alphaR)-3-Ethoxy-4-methoxy-alpha-[(methylsulfonyl)methyl]benzenemethanamine;Apremilast impurity HS093231;Benzenemethanamine, 3-ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-, (αR)-;Apremilast Impurity 58;Apremilast Impurity 83;-?[(methylsulfonyl)?methyl]?-benzenemethanamine |
| CAS: | 608142-27-4 |
| MF: | C12H19NO4S |
| MW: | 273.35 |
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| Product Categories: | |
| Mol File: | 608142-27-4.mol |
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine Chemical Properties
| Boiling point | 469.6±45.0 °C(Predicted) |
| density | 1.195±0.06 g/cm3(Predicted) |
| pka | 6.84±0.10(Predicted) |
Safety Information
(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine Usage And Synthesis
| Uses | (αR)?-3-?Ethoxy-?4-?methoxy-?α-?[(methylsulfonyl)?methyl]?-benzenemethanamine is a reagent used in the synthesis of Apremilast, a potent and active tumor necrosis factor inhibitor. |
(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine Preparation Products And Raw materials
| Raw materials | 1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)-N-(trimethylsilyl)ethylamine-->3-Ethoxy-4-methoxy benzonitrile-->3-Ethoxy-4-methoxybenzaldehyde-->3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine-->(R)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine (R)-2-acetamido-4-methylpentanoate-->1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethenamine-->Isovanillin |
| Preparation Products | (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethanaMine |
