Introduction：Basic information about (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine CAS 877399-00-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Basic information
| Product Name: | (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine |
| Synonyms: | (R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine;[5-Bromo-3-[(1R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine;[5-Bromo-3-[[(R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-2-yl]amine;(R)-5-BroMo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylaMine;(R)-5-broMo-3-[1-(2,6-dichloro-3-fluoropehnyl)ethoxy]pyridin-2-aMine;Crizotinib Impurity 3;InterMediate Ⅰof Crizotinib (R)-5-broMo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-aMine;2-PyridinaMine, 5-broMo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]- |
| CAS: | 877399-00-3 |
| MF: | C13H10BrCl2FN2O |
| MW: | 380.04 |
| EINECS: | 700-798-7 |
| Product Categories: | intermediate;877399-00-3 |
| Mol File: | 877399-00-3.mol |
|
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Chemical Properties
| Melting point | 107.0 to 111.0 °C |
| Boiling point | 423.4±40.0 °C(Predicted) |
| density | 1.643 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | powder to crystal |
| pka | 5.55±0.10(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | InChI=1S/C13H10BrCl2FN2O/c1-6(11-8(15)2-3-9(17)12(11)16)20-10-4-7(14)5-19-13(10)18/h2-6H,1H3,(H2,18,19)/t6-/m1/s1 |
| InChIKey | URFUZAZEKBBCEY-ZCFIWIBFSA-N |
| SMILES | C1(N)=NC=C(Br)C=C1O[C@@H](C1=C(Cl)C=CC(F)=C1Cl)C |
Safety Information
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Usage And Synthesis
| Chemical Properties | Pale yellow solid |
| Uses | (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine is used in preparation of Crizotinib intermediate. |
(R)-5-bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine Preparation Products And Raw materials
