1-(3-Chlorophenyl)piperazine hydrochloride CAS 65369-76-8

Introduction：Basic information about 1-(3-Chlorophenyl)piperazine hydrochloride CAS 65369-76-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

1-(3-Chlorophenyl)piperazine hydrochloride Basic information

• Product Name: 1-(3-Chlorophenyl)piperazine hydrochloride
• Synonyms: 1-(3-CHLOROPHENYL)PIPERAZINE 2HCL;1-(3-Chlorophenyl)piperazine hydrochloride,97%;N-(3-Chlorophenyl) Piperazine HCl;1-(3-Chlorophenyl)piperazine hydrochloride;1-(3-CHLOROPHENYL)-PIPERAZINE HCL (MCLPPB);Piperazine, 1-(3-chlorophenyl)-, hydrochloride;1-(3-Chlorophenyl)piperidine/hydrochloric acid,(1:x);1-(3-Chlorophenyl)piperazine hydrochloride ,98%
• CAS: 65369-76-8
• MF: C10H14Cl2N2
• MW: 233.14
• EINECS: 265-718-0
• Product Categories: Serotonin receptor;Piperazines;API intermediates
• Mol File: 65369-76-8.mol

1-(3-Chlorophenyl)piperazine hydrochloride Chemical Properties

• Melting point: 210-214 °C (dec.)(lit.)
• density: 1,193g/cm
• refractive index: 1,598-1,600
• Fp: 9℃
• storage temp.: Store at RT
• solubility: methanol: soluble
• form: Solid
• color: Pale brown
• Stability: Hygroscopic
• Major Application: forensics and toxicology
• InChI: 1S/C10H13ClN2.ClH/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13;/h1-3,8,12H,4-7H2;1H
• InChIKey: MHXPYWFZULXYHT-UHFFFAOYSA-N
• SMILES: [Cl-].Clc1cc(ccc1)[N+H]2CCNCC2
• CAS DataBase Reference: 65369-76-8(CAS DataBase Reference)

Safety Information

• Hazard Codes: Xi,Xn,T,F
• Risk Statements: 36/37/38-22-39/23/24/25-23/24/25-11
• Safety Statements: 26-36-24/25-45-36/37-16-7
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29339900
• Storage Class: 3 - Flammable liquids
• Hazard Classifications: Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Flam. Liq. 2 STOT SE 1

1-(3-Chlorophenyl)piperazine hydrochloride Usage And Synthesis

Chemical Properties

Off-white solid

Uses

Chlorophenyl Piperazine Hydrochloride Salt is a useful intermediate for organic synthesis and other chemical properties. Trazodone impurity.

General Description

1-(3-Chlorophenyl)-piperazine, also known as meta-chlorophenylpiperazine or mCPP, is a designer drug analog of aryl-substituted piperazines. A stimulant, serotonin antagonist and reuptake inhibitor (SARU), mCPP can also be detected as a primary urinary metabolite of the antidepressant drug trazadone. This certified solution standard is suitable for use in piperazine testing methods by LC/MS or GC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.

Biological Activity

5-HT 2C/2B receptor agonist/partial agonist; displays some activity at 5-HT 2A and 5-HT 1 receptors. pEC 50 values are 7.09, 7.2, 6.65, 5.9 and 6.5 for human recombinant 5-HT 2C , 2B and 2A , bovine 5-HT 1A and rat 5-HT 1B receptors respectively. Suppresses locomotor activity in rats in vivo .