1,2,3,4-Tetrahydro-1-naphthol CAS 529-33-9

Introduction：Basic information about 1,2,3,4-Tetrahydro-1-naphthol CAS 529-33-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

1,2,3,4-Tetrahydro-1-naphthol Basic information

• Product Name: 1,2,3,4-Tetrahydro-1-naphthol
• Synonyms: 1,2,3,4-tetrahydro-1-naphthaleno;1,2,3,4-Tetrahydro-1-naphthalenol;1,2,3,4-tetrahydro-1-naphtho;1,2,3,4-tetrahydro-1-napthol;1,2,3,4-Tetrahydro-alpha-naphthol;(S)-Tetralin-1-ol;(S)-Tetralin-1β-ol;1-Tetralinol
• CAS: 529-33-9
• MF: C10H12O
• MW: 148.2
• EINECS: 208-459-0
• Product Categories: Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols
• Mol File: 529-33-9.mol

1,2,3,4-Tetrahydro-1-naphthol Chemical Properties

• Melting point: 28-32 °C
• Boiling point: 102-104 °C2 mm Hg(lit.)
• density: 1.09 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.564(lit.)
• Fp: >230 °F
• storage temp.: Sealed in dry,Room Temperature
• solubility: 5.09g/l
• form: powder to lump to clear liquid
• pka: 14.33±0.20(Predicted)
• color: White or Colorless to Light yellow
• Specific Gravity: 1.090
• BRN: 2046227
• Cosmetics Ingredients Functions: PERFUMING
• InChI: 1S/C10H12O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10-11H,3,5,7H2
• InChIKey: JAAJQSRLGAYGKZ-UHFFFAOYSA-N
• SMILES: OC1CCCc2ccccc12
• LogP: 1.980
• CAS DataBase Reference: 529-33-9(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenol, 1,2,3,4-tetrahydro-(529-33-9)
• EPA Substance Registry System: 1-Naphthalenol, 1,2,3,4-tetrahydro- (529-33-9)

Safety Information

• Hazard Codes: Xn
• Risk Statements: 22-36/37/38
• Safety Statements: 22-24/25-37/39-26
• WGK Germany: 3
• RTECS: QL5075000
• TSCA: TSCA listed
• HS Code: 29062900
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral

1,2,3,4-Tetrahydro-1-naphthol Usage And Synthesis

Chemical Properties

clear colourless to slightly brown viscous liquid

Uses

1,2,3,4-Tetrahydro-1-naphthol was used as chiral probe to examine the role of three aromatic residues in enzyme-substrate interactions at the sulfuryl acceptor binding site of aryl sulfotransferase IV enzyme.

Synthesis Reference(s)

The Journal of Organic Chemistry, 61, p. 1493, 1996 DOI: 10.1021/jo951219c

General Description

(R)-(-)-enantiomer of 1,2,3,4-Tetrahydro-1-naphthol is a substrate for aryl sulfotransferase (AST) IV enzyme and (S)-(+)-1,2,3,4-tetrahydro-1-naphthol is a competitive inhibitor of AST IV-catalyzed sulfation of 1-naphthalenemethanol. It is the major urinary metabolite of tetralin.

1,2,3,4-Tetrahydro-1-naphthol Preparation Products And Raw materials

• Raw materials: 1,2,3,4-Tetrahydronaphthalene-->[1,1'-Binaphthalene]-1,1'(2H,2'H)-diol, 3,3',4,4'-tetrahydro--->1,2,3,4-tetrahydro-1-naphthyl hydroperoxide-->1,2,3,4-TETRAHYDRO-2-NAPHTHOL-->1,2-DIHYDRONAPHTHALENE
• Preparation Products: Brodifacoum-->Flocoumafen-->Coumatetralyl-->5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid-->8-BROMO-3,4-DIHYDRO-2H-NAPHTHALEN-1-ONE-->(R)-(-)-1,2,3,4-TETRAHYDRO-1-NAPHTHOL-->5,6,7,8-TETRAHYDRO-1-NAPHTHOL-->2,3,4,5-Tetrahydro-1H-benzo[b]azepine-->1,2,3,4-Tetrahydro-1-naphthylamine-->2,3-Dihydro-1,4-naphthoquinone-->(S)-(+)-1,2,3,4-Tetrahydro-1-naphthol