1,3-Dichloro-2-propanol CAS 96-23-1

Introduction：Basic information about 1,3-Dichloro-2-propanol CAS 96-23-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

1,3-Dichloro-2-propanol Basic information

• Product Name: 1,3-Dichloro-2-propanol
• Synonyms: α,γ-dichlorohydrin;SYM-GLYCEROL DICHLOROHYDRIN;1,3-Dichloro-2-propanol, 98+%;4-(4-Chlorobenzoyl)-3,5-Dichlorotoluene;1,3-Dichloro-2-propanol1,3-DC;1,3-Dichloro-2-propanol1,3-DCP;1.3-Dichlorop;1,3-DICHLORO-2-PROPANOL, 1X1ML, MEOH, 20 00UG/ML
• CAS: 96-23-1
• MF: C3H6Cl2O
• MW: 128.99
• EINECS: 202-491-9
• Product Categories: Pyrazoles,Pyrazines;Hard resin and nitrocellulose solvent;Industrial/Fine Chemicals;Alpha Sort;D;DAlphabetic;Benzene derivates;Aliphatics;Alcohols;Building Blocks;C2 to C6;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;DIA - DIC;Volatiles/ Semivolatiles;Mutagenesis Research Chemicals;Isotope Labelled Compounds
• Mol File: 96-23-1.mol

1,3-Dichloro-2-propanol Chemical Properties

• Melting point: -4 °C
• Boiling point: 174.3 °C(lit.)
• density: 1.363 g/mL at 20 °C
• vapor pressure: 1.5hPa at 20℃
• refractive index: n20/D 1.483(lit.)
• Fp: 186 °F
• storage temp.: 2-8°C
• solubility: water: soluble10 part
• pka: 12.87±0.20(Predicted)
• form: Liquid
• color: Clear colorless to slightly yellow
• Water Solubility: soluble. >=10 g/100 mL at 23 ºC
• Merck: 14,3074
• BRN: 1732063
• Dielectric constant: 47.2（0℃）
• InChI: 1S/C3H6Cl2O/c4-1-3(6)2-5/h3,6H,1-2H2
• InChIKey: DEWLEGDTCGBNGU-UHFFFAOYSA-N
• SMILES: OC(CCl)CCl
• LogP: 0.8 at 20℃
• CAS DataBase Reference: 96-23-1(CAS DataBase Reference)
• IARC: 2B (Vol. 101) 2013
• NIST Chemistry Reference: 2-Propanol, 1,3-dichloro-(96-23-1)
• EPA Substance Registry System: 1,3-Dichloro-2-propanol (96-23-1)

Safety Information

• Hazard Codes: T,F
• Risk Statements: 45-21-25-39/23/24/25-23/24/25-11
• Safety Statements: 53-45-36/37-16
• RIDADR: UN 2750 6.1/PG 2
• WGK Germany: 3
• RTECS: UB1400000
• F: 10
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: II
• HS Code: 29055910
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
• Hazard Classifications: Acute Tox. 3 Oral Acute Tox. 4 Dermal Carc. 1B
• Hazardous Substances Data: 96-23-1(Hazardous Substances Data)

1,3-Dichloro-2-propanol Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Chemical Properties

There are 4 isomers of dichloropropanols 1,3-dichloro-2-propanol (96-23-1) and “dichloropropanols”(26545-73-3) are citations in environmental regulations:C3H6OCl2 is a colorless viscous liquid with a chloroformlike odor. Slightly soluble in water. 1,3-Dichloro-2-propanol:

Uses

A labelled chloropropanol which shows toxic effects.

Uses

A chloropropanol which shows toxic effects.

Uses

1,3-Dichloro-2-propanol biotransformation to epichlorohydrin by the whole cells of recombinant Escherichia coli via resin-based in situ product removal has been investigated. It is used in the synthesis of glycerol, in the production of plastics and textiles and in the synthesis of pharmaceuticals. Also used as a solvent and as a cement for celluloid. It is also present in some foods, e.g. soy sauce, soup spices and instant soups, from hydrolization of proteins.

Definition

ChEBI: 1,3-dichloropropan-2-ol is a secondary alcohol that is isopropanol in which one hydrogen of each methyl group is substituted by a chlorine. A liquid at room temperature (melting point -4℃, boiling point 174℃ at 760 mm Hg), it is used as a solvent for hard resins and nitrocellulose. It has a role as a protic solvent and a cross-linking reagent. It is a secondary alcohol and an organochlorine compound.

General Description

Colorless to yellow slightly viscous liquid with an ethereal odor.

Air & Water Reactions

Water soluble.

Reactivity Profile

Sensitive to heat. Incompatible with oxidizers. Also incompatible with strong acids, strong reducing agents, acid chlorides and acid anhydrides.

Fire Hazard

1,3-Dichloro-2-propanol is combustible.

Flammability and Explosibility

Not classified

Safety Profile

Suspected carcinogen. Poison by ingestion and inhalation. Moderately toxic by skin contact. Human mutation data reported. A skin irritant. Action may be similar to that of carbon tetrachloride, but more irritating to mucous membranes. Flammable when exposed to heat, flame, or oxidizers. To fight fire, use alcohol foam, dry chemical, fog, mist, or spray. Dangerous; when heated to decomposition it emits highly toxic fumes of Cl and phosgene.

Potential Exposure

It is used as a solvent for hard resinsand nitrocellulose; in the manufacture of photographicchemicals and lacquer; as a cement for celluloid; and as abinder of water colors. It occurs in effluents from glyceroland halohydrin production plants.

Shipping

UN2750 1,3-Dichloropropanol-2, Hazard Class:6.1; Labels: 6.1-Poisonous materials

Incompatibilities

Incompatible with oxidizers (chlorates,nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires orexplosions. Keep away from alkaline materials, strongacids, acid anhydrides, strong bases

Toxics Screening Level

The current initial threshold screening level (ITSL) for 1,3-dichloro-2-propanol is 3 μg/m3based on an annual averaging time.

1,3-Dichloro-2-propanol Preparation Products And Raw materials

• Raw materials: Epichlorohydrin-->Allyl chloride-->hypochlorous acid-->10,10-Oxybisphenoxarsine
• Preparation Products: 1,3-Dichloroacetone-->1,2,3-Trichloropropane-->1,3-diiodopropan-2-ol-->GLYCIDYL METHYL ETHER-->Iodixanol-->Glycidol-->Oxiranemethanamine-->(S)-4-Chloro-3-hydroxybutyronitrile-->Sodium 3-Chloro-2-hydroxypropanesulfonate-->1,3-BIS(BENZYLOXY)-2-PROPANOL-->BIS(1,3-DICHLORO-2-PROPYL)PHOSPHATE-->2-hydroxypropane-1,3-diyl diacetate-->(R)-4-Chloro-3-hydroxybutyronitrile