Introduction：Basic information about 1,4-Diamino anthraquinone CAS 128-95-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
1,4-Diamino anthraquinone Basic information
| Product Name: | 1,4-Diamino anthraquinone |
| Synonyms: | 1,4-diamino-10-anthracenedione;1,4-diamino-9,10-anthracenedione;1,4-Diamino-9,10-anthraquinone;1,4-Diaminoanthra-9,10-quinone;1,4-Diaminoanthrachinon;1,4-diamino-anthraquinon;1,4-diaminoanthraquinone(ci61100);CI 61100 |
| CAS: | 128-95-0 |
| MF: | C14H10N2O2 |
| MW: | 238.24 |
| EINECS: | 204-922-6 |
| Product Categories: | Building Blocks;C13 to C14;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks;Solvent Dyestuff;Amine Monomers;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Indazoles;Intermediates of Dyes and Pigments;Aminoanthraquinones;Anthraquinones;Highly Purified Reagents;Other Categories;Refined Products by Sublimation;Monomers;Primary Amines |
| Mol File: | 128-95-0.mol |
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1,4-Diamino anthraquinone Chemical Properties
| Melting point | 265-269 °C(lit.) |
| Boiling point | 380.84°C (rough estimate) |
| density | 1.44 g/cm3 (20℃) |
| vapor pressure | <1 hPa (25 °C) |
| refractive index | 1.6500 (estimate) |
| Fp | 340 °C |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in benzene, pyridine, the difficulties, slightly soluble in hot aniline acetate, ethanol. |
| pka | 1.17±0.20(Predicted) |
| form | Solid |
| color | Dark Violet to Black |
| PH | 7 (H2O, 20℃) |
| Water Solubility | 228.7ug/L(25 ºC) |
| BRN | 2216556 |
| Stability: | Light Sensitive |
| Cosmetics Ingredients Functions | COLORANT
HAIR DYEING |
| Cosmetic Ingredient Review (CIR) | 1,4-Diamino anthraquinone (128-95-0) |
| InChI | 1S/C14H10N2O2/c15-9-5-6-10(16)12-11(9)13(17)7-3-1-2-4-8(7)14(12)18/h1-6H,15-16H2 |
| InChIKey | FBMQNRKSAWNXBT-UHFFFAOYSA-N |
| SMILES | Nc1ccc(N)c2C(=O)c3ccccc3C(=O)c12 |
| LogP | 3.000 |
| CAS DataBase Reference | 128-95-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,4-Diaminoanthraquinone(128-95-0) |
| EPA Substance Registry System | 1,4-Diaminoanthraquinone (128-95-0) |
Safety Information
| Risk Statements | 22 |
| Safety Statements | 22-36/37 |
| WGK Germany | 2 |
| RTECS | CB6300000 |
| Autoignition Temperature | >400 °C |
| TSCA | TSCA listed |
| HS Code | 29223990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Skin Sens. 1 |
| Toxicity | LD50 orally in Rabbit: 5790 mg/kg |
1,4-Diamino anthraquinone Usage And Synthesis
| Chemical Properties | Violet powder |
| Chemical Properties | 1,4-Diaminoanthraquinones (DAAQs) are an active substance. Because of its quinone function (reduction), two amine functions (oxidation) and aromatic base structures are combined that stabilize the reduced and oxidized species via electron delocalization. Therefore， they have five different electrochemical oxidation states: a neutral state, two reduced states, and two oxidized states. However, their practical availability is limited due to their low solubility in commonly used polar organic solvents. |
| Uses | Use as the intermediate of synthetic dyes. Use anthraquinone reductive dyes and dispersal dyes and acid dyes and intermediates. Itself to disperse dyestuffs purple. 1,4-Diaminoanthraquinone oxidized with different metal atoms gives rise to conducting coordination polymers consisting of difunctional ligand molecules linked by metal atoms. 1, 4-diaminoanthraquinone has solar cell applications. A hybrid Si/poly (1, 4-diaminoanthraquinone) photoconductive diode for optical sensor applications. Acts as the sequential incorporation of the mediator in electrochemical sensing of glucose on a gold electrode. |
| Uses | As an anthraquinone derivative, 1,4-Diamino anthraquinone is a potent and selective protein kinase CK1 delta inhibitor. Studies suggest that it has potential solar cell applications. 1,4-Diamino anthraquinone can be used in studies as a potential competitive non-peptidic inhibitor of HIV-1 proteinase. |
| Synthesis | 1,4-Diaminoanthraquinone is prepared by hydroxylreplacement from 1,4-dihydroxyanthraquinonevia the 2,3-dihydro compound and subsequentoxidation of the intermediate 2,3-dihydro-1,4-diaminoanthraquinone . |
| Purification Methods | Purify the anthraquinone by thin-layer chromatography on silica gel using toluene/acetone (9:1) as eluent. The main band is scraped off and extracted with MeOH. The solvent is evaporated, and the quinone is dried in a drying pistol [Land et al. J Chem Soc, Faraday Trans 1 72 2091 1976]. It crystallises from EtOH (m 269o) in dark violet crystals. Store it in sealed ampoules in the dark. [Beilstein 14 H 197, 14 II 113, 14 III 437, 14 IV 458.] |
| Properties and Applications | | Standard | Ironing Fastness | Light Fastness | Persperation Fastness | Washing Fastness | | Fading | Stain | Fading | Stain | Fading | Stain | | ISO | 4 | 2 | 5-6 | 5 | 5 | 4-5 | 5 | |
1,4-Diamino anthraquinone Preparation Products And Raw materials
| Raw materials | Sodium hydroxide-->Sodium bicarbonate-->FUMING SULFURIC ACID-->Sulfur-->Hydroquinone-->4-Nitroaniline-->1,4-Dihydroxyanthraquinone-->2,4-Diaminotoluene-->1,4-Dihydroxyanthraquinone-->Nitrobenzene |
| Preparation Products | PLUMBAGIN-->VAT BLACK 27-->Vat Brown 1-->Disperse Violet 26-->Vat Brown BR-->1,4-bis[(3-chloro-2-hydroxypropyl)amino]anthraquinone-->Disperse Violet 28-->Disperse Blue 60-->1-amino-4-[[4-[(dimethylamino)methyl]phenyl]amino]anthraquinone-->1-BROMOANTHRACENE-->Disperse Blue 14-->Solvent Green 3-->1,4-Diamino-2,3-dihydroanthraquinone |
