1-BROMO-2,3,5,6-TETRAFLUOROBENZENE CAS 1559-88-2

Introduction：Basic information about 1-BROMO-2,3,5,6-TETRAFLUOROBENZENE CAS 1559-88-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

1-BROMO-2,3,5,6-TETRAFLUOROBENZENE Basic information

• Product Name: 1-BROMO-2,3,5,6-TETRAFLUOROBENZENE
• Synonyms: BROMO-2,3,5,6-TETRAFLUOROBENZENE;1-BROMO-2,3,5,6-TETRAFLUOROBENZENE;3-BROMO-1,2,4,5-TETRAFLUOROBENZENE;1-Bromo-2,3,5,6-tetrafluorbenzene;Benzene, 3-bromo-1,2,4,5-tetrafluoro-;1-Bromo-2,3,5,6-tetrafluorobenzene 99%;1-Bromo-2,3,5,6-tetrafluorobenzene99%;1-Bromo-2,3,5,6-tetrafluorobenzene,2,3,5,6-Tetrafluorobromobenzene
• CAS: 1559-88-2
• MF: C6HBrF4
• MW: 228.97
• EINECS: 216-327-9
• Product Categories: Benzene series;Aryl;C6;Halogenated Hydrocarbons
• Mol File: 1559-88-2.mol

1-BROMO-2,3,5,6-TETRAFLUOROBENZENE Chemical Properties

• Boiling point: 143-143.5 °C(lit.)
• density: 1.883 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.469(lit.)
• Fp: 129 °F
• storage temp.: Sealed in dry,Room Temperature
• form: clear liquid
• color: Colorless to Almost colorless
• Specific Gravity: 1.883
• Water Solubility: Not miscible or difficult to mix in water.
• CAS DataBase Reference: 1559-88-2(CAS DataBase Reference)

Safety Information

• Hazard Codes: Xi,Xn
• Risk Statements: 10-36/37/38-22
• Safety Statements: 16-26-36/37/39-37/39
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 3
• Hazard Note: Irritant
• HazardClass: 3
• PackingGroup: III
• HS Code: 29039990

1-BROMO-2,3,5,6-TETRAFLUOROBENZENE Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

1-Bromo-2,3,5,6-tetrafluorobenzene is used to produce 1,2,4,5-tetrafluoro-3-hept-1-ynyl-benzene. It is also used as a pharmaceutical intermediate.

Synthesis

Potassium salt of 2,3,5,6-tetrafluorobenzoic acid (100 g) was added to dimethylformamide (250 ml) and stirred in a glass reactor equipped with a mechanical stirrer, a dropping funnel, a separator, a Liebig condenser, an adapter and a receiving flask, the reaction mixture was heated to 140 ??C and bromotrichloromethane (85 g) was added in such a way as to maintain a 140-143 ??C temperature while distilling out the resulting product. This process was continued until the end of the outgassing. The distillate was mixed with the cube and washed with two volumes of 15% perchloric acid. The lower (organic) layer was separated, hydrodistilled, then dried and distilled with CaCl2. 1-Bromo-2,3,5,6-tetrafluorobenzene (89 g) was obtained with a boiling point of 144??C and a yield of 91%.

1-BROMO-2,3,5,6-TETRAFLUOROBENZENE Preparation Products And Raw materials

• Raw materials: 2,3,5,6-TETRAFLUOROTHIOPHENOL-->Bromopentafluorobenzene-->4-BROMOTETRAFLUOROPHENYLHYDRAZINE-->1,4-DIBROMOTETRAFLUOROBENZENE-->1,2,4,5-Tetrafluorobenzene-->2,3,5,6-Tetrafluorobenzoic acid-->Sodium benzenolate
• Preparation Products: 1,1'-Biphenyl, 2,2',3,3',4,4',5,6,6'-nonafluoro--->Bromobenzene