Introduction：Basic information about 2-(1-Cyclohexenyl)ethylamine CAS 3399-73-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2-(1-Cyclohexenyl)ethylamine Basic information
| Product Name: | 2-(1-Cyclohexenyl)ethylamine |
| Synonyms: | 1-CYCLOHEXENE-1-ETHANAMINE;1-CYCLOHEXENE-2-ETHANAMINE;2-AMINOETHYL-1-CYCLOHEXENE;2-(1-CYCLOHEXENYL)ETHYLAMINE;CYCLOHEXENYLETHYLAMINE;RARECHEM AN KA 1280;1-Cyclohexen-1-ylethylamine;2-(1-Cyclohexen-1-yl)ethanamine |
| CAS: | 3399-73-3 |
| MF: | C8H15N |
| MW: | 125.21 |
| EINECS: | 222-267-4 |
| Product Categories: | Pharmaceutical Intermediates |
| Mol File: | 3399-73-3.mol |
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2-(1-Cyclohexenyl)ethylamine Chemical Properties
| Melting point | -55 °C |
| Boiling point | 53-54 °C/2.5 mmHg (lit.) |
| density | 0.898 g/mL at 25 °C (lit.) |
| refractive index | 1.486-1.488 |
| Fp | 57 °C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 10.94±0.10(Predicted) |
| form | clear liquid |
| color | Colorless to Light yellow |
| Sensitive | Air Sensitive |
| BRN | 774030 |
| Stability: | Light Sensitive |
| InChI | 1S/C8H15N/c9-7-6-8-4-2-1-3-5-8/h4H,1-3,5-7,9H2 |
| InChIKey | IUDMXOOVKMKODN-UHFFFAOYSA-N |
| SMILES | NCCC1=CCCCC1 |
| CAS DataBase Reference | 3399-73-3(CAS DataBase Reference) |
| EPA Substance Registry System | 1-Cyclohexene-1-ethanamine (3399-73-3) |
Safety Information
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 28A-26-45-36/37/39 |
| RIDADR | 2735 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29213000 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Flam. Liq. 3
Skin Corr. 1B |
2-(1-Cyclohexenyl)ethylamine Usage And Synthesis
| Chemical Properties | CLEAR COLOURLESS TO LIGHT YELLOW LIQUID |
| Uses | 2-(1-Cyclohexenyl)ethylamine has been employed:
- as substrate for allylic hydroxylation reaction
- in preparation of thin films and single crystals of 2-(1-cyclohexenyl)ethyl ammonium lead iodide, used to fabricate optoelectronic-compatible heterostructures
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| Synthesis | 125 ml of ethylamine was placed in a 250 ml three-necked flask, which had previously been flushed with argon, at -70 ° C. 6.27 g (50 mmol) of 2-phenylethylamine was added. The resulting clear, colorless solution was metered in with 1.14 g (164.2 mmol) of Li powder; the solution turned dark blue 5 minutes after the onset of turbidity. After stirring for 2 hours at -70 ° C, the mixture was warmed to -30 ° C. Then another 0.24 g (34.6 mmol) of Li powder was added. After stirring again at -30 ° C. for 2 hours, the cooling bath was removed. The reaction mixture was allowed to warm to room temperature overnight. The reaction mixture was then given 25 ml of abs. After that, a gray suspension formed. After stirring for 20 minutes at room temperature, 25 ml of water was slowly added (exothermic temperature 40 ° C.). The excess ethylamine was then distilled off at 40 °C. The distillation residue was evaporated to dryness. Then, 100 ml of water was added and extracted 3 times with 80 ml chloroform. The combined organic phases were dried over Na?SO?, filtered, and evaporated. The 2-(1-Cyclohexenyl)ethylamine was obtained in a GC yield of 69.8%. |
| Toxics Screening Level | The ITSL for cyclohexenylethylamine has been changed from 0.04 μg/m3 to 0.1 μg/m3based on an annual averaging time. |
2-(1-Cyclohexenyl)ethylamine Preparation Products And Raw materials
| Preparation Products | 2-CYCLOHEXYL-ETHYLAMINE HYDROCHLORIDE-->1-Cyclohexene-1-acetonitrile-->1H-Isoindole-1,3(2H)-dione, 2-[2-(1-cyclohexen-1-yl)ethyl]--->CHEMBRDG-BB 6610361 |
