2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine CAS 139-40-2

Introduction：Basic information about 2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine CAS 139-40-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine Basic information

• Product Name: 2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine
• Synonyms: G-30028;GESAMIL(R);CHEMBRDG-BB 5348952;2-Chloro-4，6-bis(isopropylamino)-1，3，5-triazine;2-CHLORO-4,6-BIS(ISOPROPYLAMINO)-S-TRIAZINE;2-CHLORO-4,6-BIS(ISPROPYLAMINO)-S-TRIAZINE;2,4-bis(isopropylamino)-6-chloro-1,3,5-triazine;MILOGARD(R)
• CAS: 139-40-2
• MF: C9H16ClN5
• MW: 229.71
• EINECS: 205-359-9
• Product Categories: Standards for SupelMIPTM SPEPesticides&Metabolites;Triazines;PON - PTAnalytical Standards;Alpha sort;Chromatography;Herbicides;N-PAlphabetic;P;Pesticides&Metabolites
• Mol File: 139-40-2.mol

2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine Chemical Properties

• Melting point: 212-214°C
• Boiling point: 368.7°C (rough estimate)
• density: 1.162
• vapor pressure: 0Pa at 25℃
• refractive index: 1.6110 (estimate)
• Fp: 11 °C
• storage temp.: APPROX 4°C
• solubility: Chloroform (Heated), DMSO (Slightly), Methanol (Slightly)
• pka: 2.28±0.10(Predicted)
• Water Solubility: 8.6mg/L(22 ºC)
• Merck: 13,7904
• BRN: 747081
• Major Application: agriculture cleaning products cosmetics environmental food and beverages personal care
• InChI: 1S/C9H16ClN5/c1-5(2)11-8-13-7(10)14-9(15-8)12-6(3)4/h5-6H,1-4H3,(H2,11,12,13,14,15)
• InChIKey: WJNRPILHGGKWCK-UHFFFAOYSA-N
• SMILES: CC(C)Nc1nc(Cl)nc(NC(C)C)n1
• LogP: 3.01 at 25℃ and pH7.1
• CAS DataBase Reference: 139-40-2(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-Triazine-2,4-diamine, 6-chloro-N,N'-bis(1-methylethyl)-(139-40-2)
• EPA Substance Registry System: Propazine (139-40-2)

Safety Information

• Hazard Codes: Xn;N,N,Xn,T,F
• Risk Statements: 40-50/53-39/23/24/25-23/24/25-11
• Safety Statements: 36/37-60-61-45-24-16-7
• RIDADR: UN 3077
• WGK Germany: 3
• RTECS: XY5300000
• TSCA: TSCA listed
• HazardClass: 9
• PackingGroup: III
• HS Code: 29336990
• Storage Class: 13 - Non Combustible Solids
• Hazard Classifications: Aquatic Acute 1 Aquatic Chronic 1 Carc. 2
• Hazardous Substances Data: 139-40-2(Hazardous Substances Data)
• Toxicity: LD50 orally in rats: >5000 mg/kg (Bailey, White)

2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine Usage And Synthesis

Chemical Properties

2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine is a colorless crystalline solid or powder.

Uses

2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine is used to control annual grasses and broad-leaved weeds in milo and sweet sorghum.

Uses

Herbicide.

Definition

Generic name for apreemergence herbicide containing 80% 2-chloro-4,6-bis(isopropylamino)-s-triazine.

Agricultural Uses

Herbicide: Atrazine, simazine, and propazine and their common chlorinated degradates have a common mechanism of toxicity. They have similar applications. Propazine is used for control of broadleaf weeds and annual grasses in sweet sorghum. It is applied as a spray at the time of planting or immediately following planting, but prior to weed or sorghum emergence. It is also used as a post-emergence selective herbicide on carrots, celery and fennel. Not approved for use in EU countries. Some formulations are U.S. EPA restricted Use Pesticides (RUPs).

Trade name

GEIGY® 30,028; GESAMIL®; MAXX90®; MILOCEP®; MILOGARD®[C]; MILO-PRO®; PLANTULIN®; PRIMATOL P®; PROPAZIN®; PROPINEX®; PROZINEX®

Safety Profile

Moderately toxic byingestion. Moderate eye irritation.Questionable carcinogen with experimentaltumorigenic data. When heated todecomposition it emits toxic fumes of NOxand Cl-.

Potential Exposure

A potential danger to those involvedin the manufacture, formulation and application of this tri-azine pre-emergence selective herbicide used to controlannual broadleaf weeds and grasses.

Carcinogenicity

Oral gavage of 46.4 mg/kg totwo strains of mice from 7 through 28 days of age, followedby feeding of 102 ppm for up to 18 months, produced noincrease in tumors. Subcutaneous injection of a single1000 mg/kg dose in mice of the same two strains that wereobserved for 18 months produced no carcinogenicresponse. Rats were given 0, 3, 100, or 1000 ppm ofpropazine in the diet for 2 years. At 1000 ppm, there was asignificant decrease in body weight in both sexes and anincrease in mammary tumors in females.

Environmental Fate

Soil. Undergoes microbial degradation in soil forming hydroxypropazine (Harris,1967). Dealkylation of both substituted amino groups is presumably followed by ringopening and decomposition (Hartley and Kidd, 1987). Under laboratory conditions, thehalf-lives of propazine in a Hatzenbühl soil (pH 4.8) and Neuhofen soil (pH 6.5) at 22°Cwere 62 and 127 days, respectively (Burkhard and Guth, 1981).
Groundwater. According to the U.S. EPA (1986) propazine has a high potential toleach to groundwater.
Photolytic. Irradiation of propazine in methanol afforded prometone (2-methoxy-4,6-bis(isopropylamino-s-triazine). Photodegradation of propazine in methanol did not occurwhen irradiated at wavelengths >300 nm (Pape and Zabik, 1970).
Chemical/Physical. In aqueous solutions, propazine is converted exclusively to hydroxypropazine (2-hydroxy-4,6-bisisopropylamino)-s-triazine by UV light (λ = 253.7 nm)(Pape and Zabik, 1970). In acidic aqueous soil-free systems, propazine hydrolysis is pHdependent and follows first-order kinetics. At 23.5°C, the estimated hydrolysis half-livesat pH 2.0, 3.0, 4.0 and 5.0 are 9, 36, 141 and 550 days, respectively. The rate of hydrolysiswas also found to increase and decrease in the presence of organic matter and calciumsalts, respectively (Nearpass, 1972).

Shipping

UN2763 Triazine pesticides, solid, toxic, HazardClass: 6.1; Labels: 6.1-Poisonous materials.

2,4-Bis(isopropylamino)-6-chloro-1,3,5-triazine Preparation Products And Raw materials

• Preparation Products: Prometryn-->DIPROPETRYN-->SSH-108