2,5-Dibromothiophene CAS 3141-27-3

Introduction：Basic information about 2,5-Dibromothiophene CAS 3141-27-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2,5-Dibromothiophene Basic information

• Product Name: 2,5-Dibromothiophene
• Synonyms: Thiophene,2,5-dibromo-;2,5-DIBROMO THIOPHENE 98.0%MIN;TH-2Bra;2,5-Dibromthiophen;2,5-DibroMothiophene, 95% 25GR;2,5-Dibromothiophene,95%;alpha,alpha-Dibromothiophene;NSC 4488
• CAS: 3141-27-3
• MF: C4H2Br2S
• MW: 241.93
• EINECS: 221-547-3
• Product Categories: Sulphur Derivatives;Thiophene&Benzothiophene;Thiophenes;Metal Isotopes;Thiophens;Sulfur & Selenium Compounds;Halogenated Heterocycles;Heterocyclic Building Blocks;ThiophenesBuilding Blocks;Heterocycle-oher series;bc0001
• Mol File: 3141-27-3.mol

2,5-Dibromothiophene Chemical Properties

• Melting point: -6 °C (lit.)
• Boiling point: 211 °C (lit.)
• density: 2.147 g/mL at 25 °C (lit.)
• refractive index: 1.627-1.63
• Fp: 99 °C
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• solubility: Chloroform, Methanol
• form: Liquid
• color: Clear pale yellow to brown
• Specific Gravity: 2.147
• Water Solubility: practically insoluble
• BRN: 109899
• InChI: 1S/C4H2Br2S/c5-3-1-2-4(6)7-3/h1-2H
• InChIKey: KBVDUUXRXJTAJC-UHFFFAOYSA-N
• SMILES: Brc1ccc(Br)s1
• CAS DataBase Reference: 3141-27-3(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 2,5-dibromo-(3141-27-3)
• EPA Substance Registry System: Thiophene, 2,5-dibromo- (3141-27-3)

Safety Information

• Hazard Codes: T+,Xi
• Risk Statements: 68-43-36/37/38-28-20/21
• Safety Statements: 45-36/37/39-28A-26-36
• RIDADR: UN2810
• WGK Germany: 3
• Hazard Note: Irritant
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: II
• HS Code: 29349990
• Storage Class: 10 - Combustible liquids
• Hazard Classifications: Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

2,5-Dibromothiophene Usage And Synthesis

Chemical Properties

Light Yellow Liquid

Uses

2,5-Dibromothiophene, is mainly used as pharmaceutical intermediate and synthesis intermediate.

Uses

2,5-Dibromothiophene was used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes. It was used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 58, p. 3072, 1993 DOI: 10.1021/jo00063a028
Synthesis, p. 890, 1988 DOI: 10.1055/s-1988-27740

General Description

2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .

References

[1] Tetrahedron Letters, 2010, vol. 51, # 1, p. 205 - 208
[2] Journal of Organic Chemistry, 1993, vol. 58, # 11, p. 3072 - 3075
[3] Synthesis, 1988, # 11, p. 890 - 891
[4] Journal of Organic Chemistry, 2018, vol. 83, # 2, p. 930 - 938
[5] Patent: KR2018/17709, 2018, A. Location in patent: Paragraph 0173; 0176-0179

2,5-Dibromothiophene Preparation Products And Raw materials

• Raw materials: Thiophene(SIV) (9CI)-->Potassium tert-butoxide-->Chloroform-->2,5-BIS(TRIMETHYLSILYL)THIOPHENE-->N-Bromosuccinimide-->Acetic acid-->AKOS 92422-->Thiophene, 2,5-dibromo-3-fluoro-
• Preparation Products: 5-Bromothiophene-2-carbohydrazide-->3,4-DIAMINOTHIOPHENE DIHYDROCHLORIDE-->Ethyl 5-bromothiophene-2-carboxylate-->5,5'-Dibromo-2,2'-bithiophene-->ETHYL 5-BROMOTHIOPHENE-2-CARBOXYLATE-->2,2':5',2''-TERTHIOPHENE-->2,3,5-Tribromothiophene-->2-Acetyl-5-bromothiophene-->Thiophene-2,5-dicarbonitrile-->3,5-DIBROMO-2-METHYLTHIOPHENE-->2-(TRIBUTYLSTANNYL)THIOPHENE-->5-Bromothiophenesulfonyl chloride-->5-Bromo-2-thiophenecarboxylic acid