2,5-Difluoro-4-nitrobenzoic acid CAS 116465-48-6

Introduction：Basic information about 2,5-Difluoro-4-nitrobenzoic acid CAS 116465-48-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2,5-Difluoro-4-nitrobenzoic acid Basic information

• Product Name: 2,5-Difluoro-4-nitrobenzoic acid
• Synonyms: 2,5-DIFLUORO-4-NITROBENZENECARBOXYLIC ACID;2,5-DIFLUORO-4-NITROBENZOIC ACID;2,5-Difluoro-4-Nitrobenzenecar;2,5-Difluoro-4-nitrobenzoic acid 98%;2,5-Difluoro-4-nitrobenzenecarboxylic;4-Carboxy-2,5-difluoronitrobenzene;Benzoic acid, 2,5-difluoro-4-nitro-;2,5-Difluoro-4-nitrobenzenecarboxylicaci
• CAS: 116465-48-6
• MF: C7H3F2NO4
• MW: 203.1
• Product Categories: Fluorine series;API intermediates
• Mol File: 116465-48-6.mol

2,5-Difluoro-4-nitrobenzoic acid Chemical Properties

• Melting point: 147-148
• Boiling point: 364.8±42.0 °C(Predicted)
• density: 1.661±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• form: Solid
• pka: 2.03±0.13(Predicted)
• color: White to pale green
• Water Solubility: Slightly soluble in water.
• InChI: InChI=1S/C7H3F2NO4/c8-4-2-6(10(13)14)5(9)1-3(4)7(11)12/h1-2H,(H,11,12)
• InChIKey: GPTNSBLYGCZJQV-UHFFFAOYSA-N
• SMILES: C(O)(=O)C1=CC(F)=C([N+]([O-])=O)C=C1F
• CAS DataBase Reference: 116465-48-6

Safety Information

• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-37-60
• TSCA: No
• HazardClass: IRRITANT
• HS Code: 2916399090

2,5-Difluoro-4-nitrobenzoic acid Usage And Synthesis

Uses

2,5-Difluoro-4-nitrobenzoic acid is used as a pharmaceutical intermediate.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 35, p. 2321, 1992 DOI: 10.1021/jm00090a024

2,5-Difluoro-4-nitrobenzoic acid Preparation Products And Raw materials

• Raw materials: 2,5-Difluorotoluene-->2,5-difluoro-4-nitrobenzonitrile-->1,4-DIFLUORO-2-METHYL-5-NITROBENZENE-->1-Bromo-2,5-difluorobenzene-->1,4-Difluorobenzene