2,6-Dichloroaniline CAS 608-31-1

Introduction：Basic information about 2,6-Dichloroaniline CAS 608-31-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2,6-Dichloroaniline Basic information

• Product Name: 2,6-Dichloroaniline
• Synonyms: 2,6-Dichloroaniline, 98% 100GR;2,6-Dichloroaniline, 98% 25GR;Clonidine EP Impurity C;2,6-DCA;2,6-Dichlorobenzene amide;2,6-Dichlorobenzene amine;2,6-Dichloroaniline ,99%;2,6-Dichlorophenylamine
• CAS: 608-31-1
• MF: C6H5Cl2N
• MW: 162.02
• EINECS: 210-160-5
• Product Categories: DIA - DIC;Aromatics;Alpha sort;C2 to C6;Nitrogen Compounds;Miscellaneous Reagents;Amines;AromaticsPesticides&Metabolites;Chemical Class;D;DAlphabetic;Building Blocks;C6;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 608-31-1.mol

2,6-Dichloroaniline Chemical Properties

• Melting point: 36-38 °C (lit.)
• Boiling point: 228 °C
• density: 1,275 g/cm³
• vapor pressure: <0.5 hPa ( 20 °C)
• refractive index: 1.6000 (estimate)
• Fp: >230 °F
• storage temp.: Store below +30°C.
• solubility: 1.6g/l
• pka: 0.71±0.10(Predicted)
• form: Crystalline Solid
• color: White to brown
• Odor: Aromatic odor
• Water Solubility: 1.6 g/L (20 ºC)
• BRN: 775084
• InChI: 1S/C6H5Cl2N/c7-4-2-1-3-5(8)6(4)9/h1-3H,9H2
• InChIKey: JDMFXJULNGEPOI-UHFFFAOYSA-N
• SMILES: Nc1c(Cl)cccc1Cl
• CAS DataBase Reference: 608-31-1(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2,6-dichloro-(608-31-1)
• EPA Substance Registry System: 2,6-Dichloroaniline (608-31-1)

Safety Information

• Hazard Codes: T,N,Xi
• Risk Statements: 23/24/25-33-50/53
• Safety Statements: 28-36/37-45-60-61-28A
• RIDADR: UN 3442 6.1/PG 2
• WGK Germany: 3
• RTECS: CX9862655
• F: 8
• Autoignition Temperature: >600°C
• Hazard Note: Irritant
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: II
• HS Code: 29214210
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
• Hazard Classifications: Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Aquatic Acute 1 Aquatic Chronic 1 Skin Sens. 1 STOT RE 2

2,6-Dichloroaniline Usage And Synthesis

Chemical Properties

white to brown crystalline solid

Uses

2,6-Dichloroaniline is used in the pharmaceutical industry for the synthesis of antibacterial agents of lomefloxacin, Lee uric acid and clonidine.

Definition

ChEBI: 2,6-dichloroaniline is a dichloroaniline.

Toxics Screening Level

Due to a lack of available toxicity information the ITSL is being set at the default value of 0.1 μg/m3 with annual averaging.

2,6-Dichloroaniline Preparation Products And Raw materials

• Raw materials: Carbon dioxide-->Chlorosulfonic acid-->Fluoroboric acid-->Cyclohexanone-->4-Aminobenzoic acid-->Sulfanilamide-->Benzyl benzoate-->2,6-Dichlorobenzoic acid-->Acetamide, N-acetyl-N-(2,4,6-trichlorophenyl)--->Benzenesulfonyl chloride, 4-amino-3,5-dichloro--->METHYL 4-AMINO-3,5-DICHLOROBENZOATE-->3,5-DICHLOROSULFANILAMIDE-->2,6-Dichlorobenzamide-->4-AMINO-3,5-DICHLOROBENZOIC ACID-->4-Bromo-2,6-dichloroaniline-->2,4,6-Trichloroaniline
• Preparation Products: 3,5-Dichloroaniline-->1,2,3-Trifluoro-4-nitrobenzene-->2,6-Dichlorobenzonitrile-->Disperse Orange 76-->CLONIDINE-->N-(2,6-Dichlorophenyl)acetamidine-->4-Amino-3,5-dichloroacetophenone