2-Iodothiophene CAS 3437-95-4

Introduction：Basic information about 2-Iodothiophene CAS 3437-95-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2-Iodothiophene Basic information

• Product Name: 2-Iodothiophene
• Synonyms: 2-Iodothiophene;2-Iodothiophene, 98+% 10ML;2-Iodothiophene, 98%, stab. with copper;2-IODTHIOPHENE;2-THIENYL IODIDE;2-iodo-thiophen;2-Iodothyophene;alpha-Iodothiophene
• CAS: 3437-95-4
• MF: C4H3IS
• MW: 210.04
• EINECS: 222-342-1
• Product Categories: Thiophenes & Benzothiophenes;Halogenated Heterocycles;Heterocyclic Building Blocks;ThiophenesBuilding Blocks;Heterocycle-oher series;alkyl Iodine;Halides;Thiophenes & Benzothiophenes;Thiophene&Benzothiophene;Sulphur Derivatives;Thiophenes
• Mol File: 3437-95-4.mol

2-Iodothiophene Chemical Properties

• Melting point: -40 °C (lit.)
• Boiling point: 73 °C/15 mmHg (lit.)
• density: 1.902 g/mL at 25 °C (lit.)
• refractive index: n20/D 1.651(lit.)
• Fp: 160 °F
• storage temp.: 2-8°C
• form: Liquid
• color: Clear yellow-green to red-brown
• Specific Gravity: 1.902
• Sensitive: Light Sensitive
• BRN: 104666
• InChI: 1S/C4H3IS/c5-4-2-1-3-6-4/h1-3H
• InChIKey: ROIMNSWDOJCBFR-UHFFFAOYSA-N
• SMILES: Ic1cccs1
• CAS DataBase Reference: 3437-95-4(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 2-iodo-(3437-95-4)
• EPA Substance Registry System: Thiophene, 2-iodo- (3437-95-4)

Safety Information

• Hazard Codes: Xn,Xi
• Risk Statements: 22-37/38-41-43-20/21/22-36/37/38
• Safety Statements: 26-36/37/39-36/37-27
• WGK Germany: 3
• F: 3
• TSCA: TSCA listed
• HazardClass: IRRITANT
• HS Code: 29349990
• Storage Class: 10 - Combustible liquids
• Hazard Classifications: Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 Skin Sens. 1 STOT SE 3

2-Iodothiophene Usage And Synthesis

Chemical Properties

colorless to light yellow liquid

Uses

2-Iodothiophene was used in the synthesis of (E)-and (Z)-2,3-difluoro-3-aryl substituted acrylic esters. It was also used as monomer in the preparation of thin conductive films via plasma polymerization of 2-iodothiophene.

Synthesis Reference(s)

Tetrahedron Letters, 36, p. 4883, 1995 DOI: 10.1016/0040-4039(95)00876-E

General Description

Mechanism of the fluoride-free, palladium-catalyzed cross-coupling reaction of 2-iodothiophene with potassium (E)-heptenyldimethylsilanolate has been investigated. 2-Iodothiophene participates in microwave-enhanced, rapid homogeneous-phase version of the Sonogashira reaction.

2-Iodothiophene Preparation Products And Raw materials

• Raw materials: Nitric acid-->Iodine-->Thiophene-->Mercuric Oxide-->Thiophene(SIV) (9CI)
• Preparation Products: 2-(Thien-2-yl)pyrrolidine-->2-ACETYL-5-CYANOTHIOPHENE-->2-ACETYL-5-IODOTHIOPHENE-->2-Chlorothiophene-->2-Thiophenecarbonyl chloride-->2-N-BUTYRYLTHIOPHENE-->2,5-Dibromothiophene-->1,3,5-tri(thiophen-2-yl)benzene-->3-(2-THIENYL)PYRIDINE-->ALPHA-SEXITHIOPHENE-->2-N-PROPYLTHIOPHENE-->2,5-DIIODOTHIOPHENE-->2-(Butylthio)thiophene