2-Mercapto-5-methyl-1,3,4-thiadiazole CAS 29490-19-5

Introduction：Basic information about 2-Mercapto-5-methyl-1,3,4-thiadiazole CAS 29490-19-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2-Mercapto-5-methyl-1,3,4-thiadiazole Basic information

• Product Name: 2-Mercapto-5-methyl-1,3,4-thiadiazole
• Synonyms: 2,3-Dihydro-5-methyl-1,3,4-thiadiazole-2-thione;2-Methyl-1,3,4-thiadiazole-5(4H)-thione;MMTD 2-Methyl-5-mercapto-1,3,4-thiadiazole;2-Mercapto-5-Methyl-1;MMTD)2-Mercapto-5-Methyl-1;Cefazolin IMpurity E;2-Mercapto-5-methyl-1,3,4-thiadiazole, 5-Methyl-1,3,4-thiadiazole-2-thiol;2-Methyl-5-thio-1,3,4-thiadiazole
• CAS: 29490-19-5
• MF: C3H4N2S2
• MW: 132.21
• EINECS: 249-667-1
• Product Categories: chemical additive;pharmaceutical intermediate;THIOL;API intermediates;Cephalosporins
• Mol File: 29490-19-5.mol

2-Mercapto-5-methyl-1,3,4-thiadiazole Chemical Properties

• Melting point: 185-188 °C
• Boiling point: 182.9±23.0 °C(Predicted)
• density: 1.373 (estimate)
• refractive index: 1.5500 (estimate)
• storage temp.: Sealed in dry,Room Temperature
• solubility: chloroform: soluble10mg/mL, clear to very slightly hazy, colorless
• pka: 6.49±0.40(Predicted)
• form: solid
• color: White to Off-White
• Water Solubility: 2 g/100 mL
• BRN: 606663
• InChI: InChI=1S/C3H4N2S2/c1-2-4-5-3(6)7-2/h1H3,(H,5,6)
• InChIKey: FPVUWZFFEGYCGB-UHFFFAOYSA-N
• SMILES: S1C(C)=NNC1=S
• CAS DataBase Reference: 29490-19-5(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Thiadiazole-2(3H)-thione, 5-methyl-(29490-19-5)

Safety Information

• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 37/39-26
• WGK Germany: 3
• Hazard Note: Irritant
• HS Code: 29349990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

2-Mercapto-5-methyl-1,3,4-thiadiazole Usage And Synthesis

Chemical Properties

white crystal powder

Uses

thiadiazole pharmaceutical intermediate

Uses

5-Methyl-1,3,4-thiadiazol-2-thiol (Cefazolin EP Impurity E), is a new potent nitrification inhibitors. It is also an intermediate in the synthesis of Thiazolylacetylglycine Oxime (T344230).

General Description

5-Methyl-1,3,4-thiadiazole-2-thiol is a pharmaceutical intermediate. UV and UV/H₂O₂ induced degradation of 5-methyl-1,3,4-thiadiazole-2-thiol has been investigated.

2-Mercapto-5-methyl-1,3,4-thiadiazole Preparation Products And Raw materials

• Raw materials: Ethyl acetate-->Hydrazinium hydroxide solution-->Hydrazine hydrate-->Carbon disulfide-->Potassium formate-->Acethydrazide
• Preparation Products: Methidathion-->Thidiazuron-->Cefozopran-->BISMERTHIAZOL-->5-Amino-1,3,4-thiadiazole-2-thiol-->5-Amino-1,2,3-thiadiazole-->TIADINIL-->Cefazolin-->Cefazolin sodium salt-->7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid-->benzyl 5-methyl-1,3,4-thiadiazol-2-yl sulfide-->1,3,4-Thiadiazole, 2,2'-dithiobis[5-methyl--->Ethyl 4-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]-3-oxobutanoate-->N-(5-METHYL-3-ISOXAZOLYL)-2-[(5-METHYL-1,3,4-THIADIAZOL-2-YL)SULFANYL]ACETAMIDE