Introduction：Basic information about 3-Methyl-4-nitrophenol CAS 2581-34-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
3-Methyl-4-nitrophenol Basic information
| Product Name: | 3-Methyl-4-nitrophenol |
| Synonyms: | 4-Nitro-1-hydroxy-3-methylbenzene;4-Nitro-3-phenylphenol;3-methyl-4-nitro-pheno;4-nitro-5-methylphenol;4-nitro-m-creso;5-Methyl-4-nitrophenol;m-Cresol, 4-nitro-;Phenol, 3-methyl-4-nitro- |
| CAS: | 2581-34-2 |
| MF: | C7H7NO3 |
| MW: | 153.14 |
| EINECS: | 219-952-5 |
| Product Categories: | Phenoles and thiophenoles;Aromatic Phenols |
| Mol File: | 2581-34-2.mol |
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3-Methyl-4-nitrophenol Chemical Properties
| Melting point | 125-130 °C(lit.) |
| Boiling point | 200℃（decomposition） |
| density | 1.2744 (estimate) |
| refractive index | 1.5744 (estimate) |
| Fp | 110℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Sparingly) |
| form | powder to crystal |
| pka | 7.39±0.10(Predicted) |
| color | Light yellow to Yellow to Orange |
| Water Solubility | Soluble in water(1.34g/L). |
| BRN | 1868105 |
| CAS DataBase Reference | 2581-34-2(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Nitro-5-methylphenol(2581-34-2) |
| EPA Substance Registry System | 4-Nitro-m-cresol (2581-34-2) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 20/21/22-36/37/38-22 |
| Safety Statements | 26-36/37-37/39-36-24/25 |
| RIDADR | UN 2446 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | GP2625000 |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29089000 |
3-Methyl-4-nitrophenol Usage And Synthesis
| Chemical Properties | YELLOWISH TO BEIGE CRYSTALLINE POWDER |
| Uses | 3-Methyl-4-nitrophenol is a biochemical used in the preparation of phosphorothioamidate analogues as antimalarial agents. 3-methyl-4-nitrophenol has anti-androgenic activity. PNMC significantly inhibits basal and hCG-stimulated testosterone production in rats. |
| Production Methods | m-Cresol is nitrosated in isopropanol solution and the isolated 4-nitroso-m-cresol is treated with aqueous nitric acid to oxidize itto 3-Methyl-4-nitrophenol. |
| Definition | ChEBI: A C-nitro compound in which the nitro group is attached at C-4 of m-cresol. |
3-Methyl-4-nitrophenol Preparation Products And Raw materials
| Raw materials | Nitric acid-->m-Cresol-->FENITROTHION-O-ANALOG |
| Preparation Products | Fenitrothion-->2-Methyl-4-methoxybenzenamine-->3-BROMO-5-METHOXY (1H)INDAZOLE-->5-METHOXY-1H-INDAZOLE-->5-Methoxy-2-nitrobenzoic acid-->5-Hydroxyindole-->3-Methyl-4-nitroanisole-->5-Benzyloxyindole-->TRIMETHYL THIOPHOSPHATE-->N-(4-methoxy-2-methyl-phenyl)benzamide-->Benzene, 2-methyl-1-nitro-4-propoxy- |
