Introduction：Basic information about 4-Hydroxybenzenesulfonic acid CAS 98-67-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-Hydroxybenzenesulfonic acid Basic information
| Product Name: | 4-Hydroxybenzenesulfonic acid |
| Synonyms: | 4-hydroxy-benzenesulfonicaci;4-Hydroxyphenylsulfonic acid;4-hydroxyphenylsulfonicacid;4-Phenolsulfonic acid;4-phenolsulfonicacid;Benzenesulfonic acid, p-hydroxy-;ARADUR 5003-1 BD;p-hydoroxybenzenesulfonic acid |
| CAS: | 98-67-9 |
| MF: | C6H6O4S |
| MW: | 174.17 |
| EINECS: | 202-691-6 |
| Product Categories: | Intermediates of Dyes and Pigments;Organic acids |
| Mol File: | 98-67-9.mol |
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4-Hydroxybenzenesulfonic acid Chemical Properties
| Melting point | 52 °C |
| Boiling point | 275.14°C (rough estimate) |
| density | 1.337 g/mL at 25 °C |
| vapor pressure | 69.8Pa at 20℃ |
| refractive index | n20/D 1.489 |
| solubility | Water (Slightly) |
| pka | 9.11(at 25℃) |
| form | Liquid |
| color | White to Light yellow to Light red |
| Specific Gravity | 1.337 |
| Water Solubility | Soluble in water. |
| Merck | 14,7246 |
| BRN | 1869034 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChI | 1S/C6H6O4S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4,7H,(H,8,9,10) |
| InChIKey | FEPBITJSIHRMRT-UHFFFAOYSA-N |
| SMILES | Oc1ccc(cc1)S(O)(=O)=O |
| LogP | 0.41 at 25℃ |
| CAS DataBase Reference | 98-67-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzenesulfonic acid, 4-hydroxy-(98-67-9) |
| EPA Substance Registry System | p-Phenolsulfonic acid (98-67-9) |
Safety Information
| Hazard Codes | C |
| Risk Statements | 34-68 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 2586 8/PG 3 |
| WGK Germany | - |
| RTECS | DB6970000 |
| TSCA | TSCA listed |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29089990 |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| Hazard Classifications | Met. Corr. 1
Skin Corr. 1C |
| Hazardous Substances Data | 98-67-9(Hazardous Substances Data) |
4-Hydroxybenzenesulfonic acid Usage And Synthesis
| Description | 4-hydroxybenzenesulfonic acid is an arenesulfonic acid that is phenol substituted by a sulfo group at C-4. It is functionally related to a phenol. Results obtained in a comparative study using the disulfide-bridge containing peptide deaminoarginine-vasopressin and several commonly used matrices indicate that the reduction-inhibiting efficiency of 4-hydroxy benzene sulfonic acid is comparable to that of 3-nitrobenzyl alcohol while reduction is found to be important in matrices such as thioglycerol and glycerol. Experiments conducted on peptides such as met-enkephalin and bradykinin, nucleosides and other polar compounds reveal that 4-hydroxybenzenesulfonic acid is a good solvent and has physical properties similar to glycerol. This new matrix material is a radical scavenger, is surface active, allows persistent secondary-ion beams, and produces a low background signal[1]. |
| Chemical Properties | yellowish oily liquid |
| Uses | 4-Hydroxybenzenesulfonic Acid is used as a redox-mediator in the laccase-catalyzed degradation of indigo, a textile dye. Also used in oilfield chemicals, metal working, and as a polymerization catalyst. |
| Definition | ChEBI: An arenesulfonic acid that is phenol substituted by a sulfo group at C-4. |
| Production Methods | The synthesis of 4-Hydroxybenzenesulfonic acid is as follows：Phenol (25 kg) and 96% sulfuricacid(28 kg) are heated to 50 ℃; then1.25 kg additional sulfuric acid is added and the reaction mixture is heated at 110 ℃ for 5 – 6 h. Reaction water, together with about 5% of the phenol, is distilled off during this period. Yield 95%. |
| Application | Crude 4-hydroxybenzenesulfonic acid obtained by hot sulfonation, i.e., mixed with 2- hydroxybenzenesulfonic acid, is used as such in the manufacture of synthetic tanning agents. Condensation products of phenolsulfonic acid mixtures with formaldehyde improve the dyeing properties of polyamide fibers. 4-Hydroxybenzenesulfonic acid and 2-halogenomalonic esters form the corresponding ethers, which are used in the manufacture of polyesters with improved affinity for basic dyes. If a mixture of hydroxybenzenesulfonic acids and bis(hydroxyphenyl) sulfone is condensed with formaldehyde, and hydrogensulfite is subsequently added, substances with good dispersing effects on dyes are obtained. They also are used as thinning agents for cement. Most of the 4-hydroxybenzenesulfonic acid is used as an additive for electroplating baths. By comparison, the acid is relatively unimportant as a dye intermediate. With ethylene oxide it forms poly(ethoxy)oxybenzenesulfonic acid, which can be used as a plasticizer and emulsifier. |
| Flammability and Explosibility | Non flammable |
| References | [1] J. Visentini, Michel J. Bertrand, P. M. Nguyen. “The use of 4-hydroxybenzenesulfonic acid as a reduction-inhibiting matrix in liquid secondary-ion mass spectrometry.” Rapid Communications in Mass Spectrometry 5 12 (1991): 586–590. |
4-Hydroxybenzenesulfonic acid Preparation Products And Raw materials
| Preparation Products | Sulfur-->PHENOL-FORMALDEHYDE RESIN-->Polyester resin paint-->conductive coating-composite system of acrylic copolymer and cuprous iodide-->Epoxy coal tar pitch anticorrosive coating-->Sulforhodamine B-->Epoxy zinc rich primer-->high strength adhesive HF-685-->piling adhesive YH-891-->synthetic tanning agent HV-->Epoxy polyester powder coating,mixed type-->Direct Red 243-->high temperatures structure adhesive TS812-->DAD-24 adhesive-->polyurethane adhesive for dry laminating-->high strength adhesive TS802-->rubber-asphalt cold gluing waterproof paint-->high temperature sealing putty TS747-->adhesive for ceramics and glass-->DAD-40 conductive adhesive-->high temperatures repair putty TS767-->Epoxy powder coating-->Self-crosslinking vinyl acetate copolymer latex VNA-->molding sand binder |
