Introduction：Basic information about 5alpha-Hydroxycostic acid CAS 132185-83-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
5alpha-Hydroxycostic acid Basic information
| Product Name: | 5alpha-Hydroxycostic acid |
| Synonyms: | (2R,4aR,8aR)-Decahydro-8a-hydroxy-4a-methyl-alpha,8-bis(methylene)-2-naphthaleneacetic acid;5alpha-Hydroxycostic acid;5α-Hydroxycostic acid;2-Naphthaleneacetic acid, decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-, (2R,4aR,8aR)-;5α-Hydroxycosticacid |
| CAS: | 132185-83-2 |
| MF: | C15H22O3 |
| MW: | 250.33338 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 132185-83-2.mol |
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5alpha-Hydroxycostic acid Chemical Properties
| Boiling point | 406.4±38.0 °C(Predicted) |
| density | 1.12±0.1 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 4.42±0.11(Predicted) |
| color | White to off-white |
Safety Information
5alpha-Hydroxycostic acid Usage And Synthesis
| Uses | 5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1]. |
| target | VEGF | Src | AKT | NOS | FAK | PLCγ | ERK |
| References | [1] Liang N, et, al. Two natural eudesmane-type sesquiterpenes from Laggera alata inhibit angiogenesis and suppress breast cancer cell migration through VEGF- and Angiopoietin 2-mediated signaling pathways. Int J Oncol. 2017 Jul;51(1):213-222. DOI:10.3892/ijo.2017.4004 |
5alpha-Hydroxycostic acid Preparation Products And Raw materials
