Introduction：Basic information about 6,7-Dimethoxyquinazoline-2,4-dione CAS 28888-44-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
6,7-Dimethoxyquinazoline-2,4-dione Basic information
| Product Name: | 6,7-Dimethoxyquinazoline-2,4-dione |
| Synonyms: | QUINAZOLINDIONE;2,4-Dihydroxy-6,7-dimethoxquinazoline;2,4-DIONE-6,7-DIMETHOXYQUINAZOLINE;2,4-DIHYDROXY-6,7-DIMETHOXYQUINAZOLINE;LABOTEST-BB LT00453115;1,2,3,4-TETRAHYDRO-6,7-DIMETHOXYQUINAZOLINE-2,4-DIONE;6,7-DIMETHOXY-(1H,3H)-2,4-QUINAZOLINDIONE;6,7-DIMETHOXY-2,4(1H,3H)-QUINAZOLINEDIONE |
| CAS: | 28888-44-0 |
| MF: | C10H10N2O4 |
| MW: | 222.2 |
| EINECS: | 249-288-1 |
| Product Categories: | Aromatics;Heterocycles;Building Blocks;Heterocyclic Building Blocks;Intermediates & Fine Chemicals;Pharmaceuticals;Quinolines, Quinazolines and derivatives;Quinoline&Isoquinoline;Doxazosin;Quinazolines |
| Mol File: | 28888-44-0.mol |
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6,7-Dimethoxyquinazoline-2,4-dione Chemical Properties
| Melting point | >300 °C (lit.) |
| Boiling point | 363.37°C (rough estimate) |
| density | 1.3404 (rough estimate) |
| refractive index | 1.6300 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Sparingly) |
| pka | 10.27±0.20(Predicted) |
| color | White to Off-White |
| Water Solubility | insoluble |
| BRN | 204597 |
| InChI | 1S/C10H10N2O4/c1-15-7-3-5-6(4-8(7)16-2)11-10(14)12-9(5)13/h3-4H,1-2H3,(H2,11,12,13,14) |
| InChIKey | KWNQIIMVPSMYEM-UHFFFAOYSA-N |
| SMILES | COc1cc2NC(=O)NC(=O)c2cc1OC |
| CAS DataBase Reference | 28888-44-0(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| HS Code | 29339990 |
| Storage Class | 11 - Combustible Solids |
6,7-Dimethoxyquinazoline-2,4-dione Usage And Synthesis
| Chemical Properties | brown powder |
| Uses | 6,7-Dimethoxyquinazoline-2,4-dione (Doxazosin EP Impurity D) is an intermediate in the preparation of Alfuzosin hydrochloride (A532000), an antihypertensive. |
6,7-Dimethoxyquinazoline-2,4-dione Preparation Products And Raw materials
| Preparation Products | 2-Chloro-4-amino-6,7-dimethoxyquinazoline |
