Acid Green 50 CAS 3087-16-9

Introduction：Basic information about Acid Green 50 CAS 3087-16-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Acid Green 50 Basic information

• Product Name: Acid Green 50
• Synonyms: LISSAMINE GREEN B;ACID GREEN 50;[4-[4-(dimethylamino)-alpha-(2-hydroxy-3,6-disulphonato-1-naphthyl)benzylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium inner salt sodium salt;WOOL GREEN S;12078green;acidalwoolgreenbs;acidbrilliantgreenbs;AcidgreenBS
• CAS: 3087-16-9
• MF: C27H27N2NaO7S2
• MW: 578.63
• EINECS: 221-409-2
• Product Categories: Dyes and Pigments
• Mol File: 3087-16-9.mol

Acid Green 50 Chemical Properties

• Melting point: >300°C
• density: 0.541[at 20℃]
• storage temp.: Refrigerator
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: Powder
• Colour Index: 44090
• color: Dark brown or black
• Water Solubility: 492.554g/L at 28℃
• ε(extinction coefficient): ≥10000 at 300-306nm in water at 0.005g/L ≥50000 at 236-242nm in water at 0.005g/L ≥60000 at 630-636nm in water at 0.005g/L
• λmax: 633 nm
• Stability: Incompatible with strong oxidizing agents.
• Major Application: cleaning products cosmetics food and beverages personal care
• Cosmetics Ingredients Functions: COLORANT
• InChIKey: BVUWAHIFBKMCJZ-UHFFFAOYSA-N
• SMILES: C(=C1C=C/C(=[N+](/C)\C)/C=C1)(C1C=CC(N(C)C)=CC=1)C1=C(C(S([O-])(=O)=O)=CC2=CC(S(O)(=O)=O)=CC=C12)O.[NaH]
• LogP: 0.595 at 25℃
• CAS DataBase Reference: 3087-16-9(CAS DataBase Reference)
• EPA Substance Registry System: Methanaminium, N-[4-[[4-(dimethylamino)phenyl](2-hydroxy-3,6-disulfo-1-naphthalenyl)methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, inner salt, monosodium salt (3087-16-9)

Safety Information

• Hazard Codes: Xn
• Risk Statements: 22-36/37/38
• Safety Statements: 36/37/39
• WGK Germany: 3
• RTECS: BQ1150000
• TSCA: TSCA listed
• HS Code: 32041200
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
• Toxicity: rat,LD50,oral,2gm/kg (2000mg/kg),Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979.

Acid Green 50 Usage And Synthesis

Chemical Properties	solid
Uses	Acid Green 50 is a food coloring in drinks and candles. Also used on living cells as protein stains for chemical and molecular analyses.
Preparation	(a)4-(Dichloro(4-(dimethylamino)phenyl)methyl)-N,N-dimethylbenzenamine and Naphthalen-2-ol condensation, with hair smoke sulphonated sulfuric acid, and translated into sodium salt; (b) Bis (4 – (dimethylamino) phenyl) methanoland ?3-Hydroxynaphthalene-2,7-disulfonic acid (or 7-Hydroxynaphthalene-1,3-disulfonic acid) condensation, product oxidation, and translated into sodium salt.
Biological Activity	Lissamine green also referred to as acid green 50, wool green S, food green S or green S, is used for vital staining of cornea and conjunctiva. Staining characteristics are almost similar to rose bengal dye. Lissamine green is also used to stain membrane-damaged epithelial cells. In vitro, Lissamine green B at low concentration blocks herpes simplex virus 1 (HSV-1) plaque formation.
Properties and Applications	blue light green. Blue-green powder. Soluble in cold water, easily soluble in hot water (green blue), soluble in ethanol (turquoise blue). Meet strong sulfuric acid as orange, a green light amber after diluted. Mainly used for wool, polyamide, silk dyeing. Also used in leather, food, medicine and cosmetics of shading. Standard Light Fastness Soaping Persperation Fastness Oxygen bleaching Fastness to seawater Fading Stain Fading Stain Fading Stain ISO 3 2 3 4 1 5 3 1 AATCC 2-3 3 3 2 1 1 3 3
Purification Methods	Crystallise it from EtOH/water (1:1, v/v). Irritant. [Beilstein 14 II 574.]

Acid Green 50 Preparation Products And Raw materials

• Raw materials: Disodium 2-naphthol-3,6-disulfonate-->4,4'-Bis(dimethylamino)benzhydrol-->2-Naphthol-6,8-disulfonic acid-->4-(dichloro(4-(dimethylamino)phenyl)methyl)-N,N-dimethylbenzenamine-->2-Naphthol