Calcium lactate CAS 814-80-2
Introduction：Basic information about Calcium lactate CAS 814-80-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Calcium lactate Basic information
| Product Name: | Calcium lactate |
| Synonyms: | LACTIC ACID CALCIUM SALT, TRIHYDRATE;CALCIUM LACTATE, TRIHYDRATE;2-HYDROXYPROPANOIC ACID CALCIUM SALT, TRIHYDRATE;2-hydroxy-propanoicacicalciumsalt(2:1);calciumlactate(1:2);calphosan;Calcium DL-lactate;Conclyte Ca |
| CAS: | 814-80-2 |
| MF: | C3H8CaO3 |
| MW: | 132.17 |
| EINECS: | 212-406-7 |
| Product Categories: | Food additives;Nutritional fortification substances;Food additve and acidulant |
| Mol File: | 814-80-2.mol |
Calcium lactate Chemical Properties
| solubility | Soluble in water, freely soluble in boiling water, very slightly soluble in ethanol (96 per cent). |
| PH | 7.56(1 mM solution);7.97(10 mM solution);8.28(100 mM solution);8.5(1000 mM solution) |
| Odor | Odorless |
| Major Application | pharmaceutical (small molecule) |
| Cosmetics Ingredients Functions | KERATOLYTIC ASTRINGENT BUFFERING |
| Cosmetic Ingredient Review (CIR) | Calcium lactate (814-80-2) |
| InChI | InChI=1S/C3H6O3.Ca.2H/c1-2(4)3(5)6;;;/h2,4H,1H3,(H,5,6);;; |
| InChIKey | KSDPLTNUUQNXLV-UHFFFAOYSA-N |
| SMILES | C(O)(C)C(=O)O.[Ca] |
| LogP | -0.698 (est) |
| CAS DataBase Reference | 814-80-2(CAS DataBase Reference) |
| EPA Substance Registry System | Calcium lactate (814-80-2) |
Safety Information
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| WGK Germany | WGK 1 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 814-80-2(Hazardous Substances Data) |
| Description | Calcium lactate is a black or white crystalline salt made by the action of lactic acid on calcium carbonate. It is used in foods (as an ingredient in baking powder) and given medicinally. Its E number is E327. It is created by the reaction of lactic acid with calcium carbonate or calcium hydroxide. Calcium lactate is often found in aged cheeses. Small crystals of it precipitate out when lactic acid is converted into a less soluble form by the bacteria active during the ripening process. In medicine, calcium lactate is most commonly used as an antacid and also to treat calcium deficiencies. Calcium lactate can be absorbed at various pHs and does not need to be taken with food for absorption for these reasons. Calcium lactate is added to sugar-free foods to prevent tooth decay. When added to chewing gum containing xylitol, it increases the remineralization of tooth enamel.It is also added to fresh-cut fruits such as cantaloupes to keep them firm and extend their shelf life, without the bitter taste caused by calcium chloride, which can also be used for this purpose. |
| Chemical Properties | White or almost white, crystalline or granular powder. |
| Chemical Properties | Calcium lactate occurs as white or almost white, crystalline orgranular powder. It is slightly efflorescent. |
| Uses | Calcium Lactate is the calcium salt of lactic acid which is soluble in water. it has a solubility of 3.4 g/100 g of water at 20°c and is very soluble in hot water. it is available as a monohydrate, trihydrate, and pentahydrate. the trihydrate and pentahydrate have solubili-ties of 9 g in 100 ml of water at 25°c. it contains approximately 14% calcium. it is used to stabilize and improve the texture of canned fruits and vegetables by converting the labile pectin to the less solu-ble calcium pectate. it thereby prevents structural collapse during cooking. it is used in angel food cake, whipped toppings, and meringues to increase protein extensibility which results in an increase of foam volume. it is also used in calcium fortified foods such as infant foods and is used to improve the properties of dry milk powder. |
| Uses | As a preservative in foods and beverages; in dentifrices. |
| Uses | Lactic Acid Calcium Salt is used in foods as an ingredient in baking powder. Lactic Acid Calcium Salt is also used as an antacid and also to treat calcium deficiencies. |
| Production Methods | Calcium lactate is prepared commercially by neutralization withcalcium carbonate or calcium hydroxide of lactic acid obtainedfrom fermentation of dextrose, molasses, starch, sugar, or whey. |
| Brand name | Prequist Powder (Parke-Davis). |
| Hazard | A poison. |
| Pharmaceutical Applications | Calcium lactate is used as a bioavailability enhancer and nutrientsupplement in pharmaceutical formulations. A spray-dried grade of calcium lactate pentahydrate has beenused as a tablet diluent in direct compression systems, and hasbeen shown to have good compactability. The properties of thepentahydrate form have been considered superior to those ofcalcium lactate trihydrate when used in direct compression tabletformulations. Tablet properties may be affected by the hydrationstate of the calcium lactate and particle size of the material: reducingparticle size increased crushing strength, whereas storage of tabletsat elevated temperature resulted in dehydration accompanied by areduction in crushing strength. Calcium lactate has also been used as the source of calcium ionsin the preparation of calcium alginate microspheres for controlled-release delivery of active agents. It has been shown to result in lowercalcium concentrations in the finished microspheres when comparedwith calcium acetate. Therapeutically, calcium lactate has been used in preparationsfor the treatment of calcium deficiency. |
| Safety | Calcium lactate was found to have no toxic or carcinogenic effectswhen dosed at levels of 0%, 2.5%, and 5% in drinking water tomale and female rats for 2 years. |
| storage | Calcium lactate can exist in a number of hydration states, which arecharacterized as anhydrous, monohydrate, trihydrate, and pentahydrate.Dehydration of the pentahydrate form is rapid attemperatures of 558℃ and above. Dehydration is reported to beaccompanied by some loss of crystallinity. Tablet crushingstrength was reported to be reduced following dehydration ofcalcium lactate pentahydrate. |
| Purification Methods | Crystallise it from warm water (10mL/g) by cooling to 0o. [Beilstein 3 IV 636.] |
| Incompatibilities | Calcium salts, including the lactate, can display physical incompatibilitywith phosphate in the diet or therapeutic preparations, forexample in enteral feed mixtures. |
| Regulatory Status | GRAS listed except for infant foods/formulas. Accepted as afood additive in Europe. Calcium lactate (anhydrous) is included inthe FDA Inactive Ingredients Database (vaginal, tablet). It is used inoral dosage forms. Included in vaginal pessary formulationslicensed in the UK. |
Calcium lactate Preparation Products And Raw materials
| Raw materials | Calcium carbonate-->Calcium hydroxide-->Lactic acid-->Calcium phosphate-->Magnesium hydroxide-->MAIZE POWDER MA 1.0 IRMM CERTIFIED RE-F-->L(+)-Lactic acid-->LACTICACIDBACTERIA-->D-glucose-->DL-Lactide-->(R)-Lactate |
| Preparation Products | Lactic acid-->Ferrous lactate-->Butyl lactate-->AMYL LACTATE-->ISOBUTYL LACTATE |
