CARBOXYPEPTIDASE W CAS 9046-67-7

Introduction：Basic information about CARBOXYPEPTIDASE W CAS 9046-67-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

CARBOXYPEPTIDASE W Basic information

• Product Name: CARBOXYPEPTIDASE W
• Synonyms: Yeast proteinase C;Yeast proproteinase C;Lysosomal carboxypeptidase A;E.C. 3.4.16.5;E.C. 3.4.12.1;PEPTIDYL-L-AMINO ACID HYDROXYLASE;SERINE CARBOXYPEPTIDASE;Carboxypeptidase Y (from Yeast)
• CAS: 9046-67-7
• MW: 0
• EINECS: 232-934-1
• Product Categories: enzyme;Carboxypeptidase WApplication Index;3.4.x.x Peptidases;3.x.x.x Hydrolases;Proteases&Protein Sequencing;ProteasesEnzyme Class Index;Proteolytic Enzymes and Substrates;Selective Proteolytic Enzymes
• Mol File: Mol File

CARBOXYPEPTIDASE W Chemical Properties

• storage temp.: −20°C
• form: powder
• color: white
• Water Solubility: Soluble in water.
• Specific Activity: ≥50units/mg protein

Safety Information

• Hazard Codes: Xn
• Risk Statements: 36/37/38-42
• Safety Statements: 22-24-26-36/37-45
• WGK Germany: 1
• F: 10-21
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2 Resp. Sens. 1 Skin Irrit. 2 STOT SE 3

CARBOXYPEPTIDASE W Usage And Synthesis

Uses

Carboxypeptidase Y from yeast is used for C-terminal sequencing of proteins. Also for C-terminal modification of proteins and peptides. Due to its amidase action, it is applied to the sequence analysis of peptides having amidated COOH-terminal groups such as oxytocin and vasopressin.

Biological Activity

The glycoprotein has a molecular weight of about 61,000, has a nitrogen content of 12.74%. It is a single polypeptide chain of 442 residues with 16 residues of glucosamine in the carbohydrate moiety. Lysine is at the NH2 terminus and -Asp-Ser-Thr-Leu is the COOH-terminal sequence. The principal action of the enzyme is to remove COOH-terminal residues from polypeptide chains. It is used as a vacuolar marker enzyme for studies on protein transport and localization.