| Description | Cyanidin chloride is a hydrolysis or naturally occurring compound that is found in many red berries, namely blackberry, bilberry, cherry, grapes, raspberry, and cranberry. It can slo be found in flowers and fruits that contain cyanidin-derivatives such as plums, apples, as well as red onion and red cabbage. Cyanidin chloride is reddish-purple in color, which normally changes according to the pH. |
| Production | Cyanidin chloride is produced from natural sources through extraction processes. Cyanidin chloride belongs to the anthocyanins. |
| Safety | When being used in laboratories, only qualified workers should handle the chemical. Cyanidin chloride should be stored in darkness and at low temperatures. |
| Chemical Properties | Purple powder |
| Uses | Cyanidin Chloride is a flavonoid compound that protects neuronal cells from oxidative stress. Present in tart cherries, it also contributes to antiinflammatory and antioxidant activities. |
| Definition | ChEBI: An organic anion obtained by selective deprotonation of the 3- and 5-hydroxy groups of cyanidin(1+). |
| General Description | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
| Biochem/physiol Actions | Anthocyanidin. Pigment found in several varieties of berries. Antioxidant. |
| Anticancer Research | It is a kind of anthocyanidin and a common pigment found in many red berriesincluding raspberry, grapes, acai berry, bilberry, loganberry, blackberry, hawthorn,blueberry, elderberry, cherry, and cranberry. It is an antioxidant and free radicalscavenging agent. It affects the colon cancer cell growth by inhibiting nitric oxidesynthase and COX-2 gene expression. The derivative, cyanidin-3-glucoside (C3G),plays a role in the reduction of AP-1 activation and NF-κB and phosphorylation ofMEK, MKK4, Akt, and MAPKs and blocks the activation of Fyn kinase signalingpathway and ErbB2/cSrc/FAK pathway. It is inhibits the UVB-induced COX2expression and PGE2 secretion by suppressing AP-1, NF-κB, MKK4, MEK1, andRaf-1. Cyanidin-3-galactoside and cyanidin-3-glucoside are found to be BCRPsubstrates, and cyanidin, cyanidin-3,5-diglucoside, and cyanidin-3-rutinoside arefound to be BCRP inhibitors (Wang et al. 2012). |
