Introduction：Basic information about Diisopropyl phosphite CAS 1809-20-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Diisopropyl phosphite Basic information
| Product Name: | Diisopropyl phosphite |
| Synonyms: | Diisopropyl hydrogen phosphonate;Diisopropylphosphine oxide;Isopropyl phosphonate;Isopropyl phosphonate ((C3H7O)2HPO);isopropylphosphonate;O,O-Diisopropyl phosphonate;o,o-diisopropylphosphite;o,o-diisopropylphosphonate |
| CAS: | 1809-20-7 |
| MF: | C6H15O3P |
| MW: | 166.16 |
| EINECS: | 217-317-7 |
| Product Categories: | organophosphorus compound;Miscellaneous Reagents;bc0001 |
| Mol File: | 1809-20-7.mol |
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Diisopropyl phosphite Chemical Properties
| Boiling point | 71 °C (8 mmHg) |
| density | 0.997 |
| refractive index | 1.4065-1.4085 |
| Fp | 69°C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Sparingly) |
| form | Liquid |
| color | Clear colorless |
| Specific Gravity | 1 |
| Water Solubility | soluble |
| Sensitive | Moisture Sensitive |
| InChI | InChI=1S/C6H15O3P/c1-5(2)8-10(7)9-6(3)4/h5-6,10H,1-4H3 |
| InChIKey | BLKXLEPPVDUHBY-UHFFFAOYSA-N |
| SMILES | P(=O)(OC(C)C)OC(C)C |
| CAS DataBase Reference | 1809-20-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Phosphonic acid, di-isopropyl ester(1809-20-7) |
| EPA Substance Registry System | Phosphonic acid, bis(1-methylethyl) ester (1809-20-7) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 37/39-26 |
| RIDADR | 3265 |
| RTECS | SZ7660000 |
| TSCA | TSCA listed |
| HS Code | 29209085 |
| Toxicity | guinea pig,LC50,inhalation,9010mg/m3 (9010mg/m3),LUNGS, THORAX, OR RESPIRATION: OTHER CHANGESGASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 29(11), Pg. 51, 1985. |
Diisopropyl phosphite Usage And Synthesis
| Chemical Properties | clear colourless liquid, corrosive, soluble in organic solvents such as ethanol. |
| Uses | Diisopropyl phosphite is used as antiwear lubricant additive together with triphenyl thiophosphate on T8 steel/Al2O3 ceramics. |
| Preparation | Diisopropyl phosphite is prepared by directly reacting isopropanol with phosphorus trichloride.
3(CH3)2CHOH+PCl3→[(CH3)2CHO]2POH+2HCl↑+(CH3)2CHCl
At a ratio of 3:1 (mol), continuously feed 215kg/h of isopropanol and 150kg/h of phosphorus trichloride. When mixed, this results in a violent reaction that generates hydrogen chloride gas. This gas is quickly removed from the mixing pot using vacuum mercury. The crude ester produced is then heated in a falling film type spinner deacidification device and further deacidified. The resulting product is then cooled to below 40°C and obtained with a content of 92%-95% and a yield of 95%～98%. |
| Synthesis Reference(s) | Tetrahedron Letters, 29, p. 3327, 1988 DOI: 10.1016/0040-4039(88)85153-0 |
Diisopropyl phosphite Preparation Products And Raw materials
| Raw materials | Isopropyl alcohol-->Phosphorus trichloride-->TRIISOPROPYL PHOSPHATE-->Triisopropyl phosphite |
| Preparation Products | Iprobenfos-->AMMONIUM O,O-DIISOPROPYLTHIOPHOSPHATE-->DIISOPROPYL METHYLPHOSPHONATE-->Diethyl allylphosphonate-->2,2'-DINITRODIBENZYL-->Tetraisopropyl methylenediphosphonate-->2,6-ditert-butyl-4-[di(propan-2-yloxy)phosphorylmethyl]phenol-->Methanesulfonic acid, 1,1,1-trifluoro-, [bis(1-methylethoxy)phosphinyl]methyl ester-->2-Fluoro-N-isopropylbenzaMide, 97% |
