Dithioerythritol CAS 6892-68-8
Introduction：Basic information about Dithioerythritol CAS 6892-68-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Dithioerythritol Basic information
| Product Name: | Dithioerythritol |
| Synonyms: | (S,R)-DITHIOERYTHRITOL;(r*,s*)-1,4-dimercapto-2,3-butanediol;1,4-dimercapto-,(r*,s*)-3-butanediol;1,4-dimercapto-,(theta,s)-3-butanediol;1,4-dithio-erythrito;DITHIOERYTHRITOL MOLECULAR BIOLOGY*REAGE NT;DITHIOERYTHRITOL, 99+%;DITHIOERYTHRITOL SIGMAULTRA |
| CAS: | 6892-68-8 |
| MF: | C4H10O2S2 |
| MW: | 154.25 |
| EINECS: | 229-998-8 |
| Product Categories: | Pharmaceutical Intermediates;Antioxidant;Biochemistry;Erythrose;O-Substituted Sugars;Sugar Alcohols;Sugars;proteinmod |
| Mol File: | 6892-68-8.mol |
Dithioerythritol Chemical Properties
| Melting point | 82-84 °C(lit.) |
| Boiling point | 247.65°C (rough estimate) |
| density | 1.156 (estimate) |
| refractive index | 1.5200 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: 10 mg/mL, clear, colorless |
| form | Powder |
| pka | pK1:9.5 (25°C) |
| color | White to pale yellow or beige |
| PH | 4.0-6.0 (25℃, 0.1M in H2O) |
| Water Solubility | Soluble |
| λmax | λ: 260 nm Amax: 0.400 λ: 280 nm Amax: 0.050 |
| Sensitive | Air Sensitive |
| BRN | 1719756 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChI | 1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4+ |
| InChIKey | VHJLVAABSRFDPM-ZXZARUISSA-N |
| SMILES | SC[C@H](O)[C@H](O)CS |
| CAS DataBase Reference | 6892-68-8(CAS DataBase Reference) |
| EPA Substance Registry System | 1,4-Dithioerythritol (6892-68-8) |
| Absorption | ≤0.4 at 280 in H2O at 0.1M ≤0.6 at 260 in H2O at 0.1M |
Safety Information
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-36-37/39 |
| RIDADR | UN 3335 |
| WGK Germany | 3 |
| RTECS | KF2410000 |
| F | 3-10-13-23 |
| TSCA | TSCA listed |
| HazardClass | 9 |
| HS Code | 29309070 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 3 |
| Chemical Properties | White solid |
| Uses | Reagent for the reduction of disulfide group. Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis. Cleavage of disulfide bonds in proteins |
| Uses | 1,4-Dithioerythritol is a Michael reaction acceptor; inducers of enzymes that protect against carcinogenesis: reactivity with sulfhydryl groups. |
| Uses | Reagent for maintaining ?SH groups in the reduced state; quantitatively reduces disulfides. |
| Definition | ChEBI: The meso-diastereomer of 1,4-dimercaptobutane-2,3-diol; a sulfur-containing sugar derived from the monosaccharide erythrose; and an epimer of dithiothreitol. |
| reaction suitability | reagent type: reductant |
| Purification Methods | Crystallise DTE from ether/hexane and store it in the dark at 0o. [Beilstein 1 III 2360.] |
Dithioerythritol Preparation Products And Raw materials
