Introduction：Basic information about Ethyl Azidoacetate CAS 637-81-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Ethyl Azidoacetate Basic information
| Product Name: | Ethyl Azidoacetate |
| Synonyms: | azido-aceticaciethylester;ETHYL 2-(1H-TRIAZIRIN-1-YL)ACETATE;ETHYLAZIDACETATE;ETHYL AZIDOACETATE;AZIDOACETIC-ACID-ETHYL-ESTER;ETHYL AZIDOACETATE SOLUTION, 25% IN ETHANOL;ETHYL AZIDOACETATE SOLUTION, 30% IN METHYLENECHLORIDE;ETHYL AZIDOACETATE SOLUTION, 25% IN TOLUENE |
| CAS: | 637-81-0 |
| MF: | C4H7N3O2 |
| MW: | 129.12 |
| EINECS: | 211-301-3 |
| Product Categories: | Azides;AzidesChemical Ligation;Click Chemistry;Nitrogen Compounds;Organic Azides;Organic Building Blocks |
| Mol File: | 637-81-0.mol |
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Ethyl Azidoacetate Chemical Properties
| Boiling point | 44-46°C 2mm |
| density | 1.12g/ml |
| refractive index | 1.4330 to 1.4370 |
| Fp | 25 °C |
| storage temp. | Refrigerator, under inert atmosphere |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Oil |
| color | Colourless to Pale Yellow |
| BRN | 4247209 |
| InChI | InChI=1S/C4H7N3O2/c1-2-9-4(8)3-6-7-5/h2-3H2,1H3 |
| InChIKey | HVJJYOAPXBPQQV-UHFFFAOYSA-N |
| SMILES | C(=O)(OCC)CN=[N+]=[N-] |
| CAS DataBase Reference | 637-81-0(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xn,Xi,C,F |
| Risk Statements | 1-40-36/37/38-10-67-65-63-48/20-38-11 |
| Safety Statements | 7-16-26-35-36-47-62-45-36/37 |
| RIDADR | UN 1593 6.1/PG 3 |
| WGK Germany | 2 |
| Hazard Note | Irritant/Corrosive |
| HS Code | 2929.90.5090 |
| HazardClass | 3 |
| PackingGroup | III |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Eye Irrit. 2
Flam. Liq. 2 |
Ethyl Azidoacetate Usage And Synthesis
| Uses | Ethyl Azidoacetate is an important organic substance that can undergo cyclisation reactions and is commonly used in the field of chemical synthesis.The condensation of 1-methyl-β-carboline-3-carbaldehyde with ethyl azidoacetate can be used to prepare 2-formylxanthine derivatives[1]. |
| reaction suitability | reaction type: click chemistry |
| References | [1] GLENN C. CONDIE Jan B. Synthesis of some fused β-carbolines including the first example of the pyrrolo[3,2-c]-β-carboline system[J]. Journal of Heterocyclic Chemistry, 2009, 41 4: 531-540. DOI:10.1002/jhet.5570410409. |
Ethyl Azidoacetate Preparation Products And Raw materials
| Preparation Products | 4-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBALDEHYDE-->2-(4-METHOXY-1H-PYRROLO[2,3-B]PYRIDIN-2-YL)ETHANAMINE-->(4-METHOXY-1H-PYRROLO[2,3-B]PYRIDIN-2-YL)METHANOL-->ethyl 6-bromo-4-fluoro-1H-indole-2-carboxylate-->ETHYL 4-METHOXY-1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLATE-->ETHYL 6H-FURO[2,3-B]PYRROLE-5-CARBOXYLATE-->2-(4-Methoxyphenyl)-4H-furo[3,2-b]pyrrole-5-carboxylic Acid Ethyl Ester |
